Spike_GSAS_6P protomer RBD domain bound with R1-32 Fab and ACE2 with 3:3:3 ratio
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 7ydi
Q-score: 0.296
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X
Nat Microbiol (2022) 7 pp. 1635-1649 [ DOI: doi:10.1038/s41564-022-01235-4 Pubmed: 36151403 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s-gsas/6p spike trimer (Complex from Homo sapiens)
- Heavy chain of r1-32 (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 s-gsas/6p spike trimer bound to r1-32 fab with 3:1 ratio (Complex from Homo sapiens)
- R1-32 fab (Complex)
- Zinc ion (65 Da, Ligand)
- Light chain of r1-32 (22 kDa, Protein from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Spike_GSAS_6P and R1-32 Fab with 3to1 ratio
Resolution: 4.75 Å
EM Method: Single-particle
Fitted PDBs: 7ydy
Q-score: 0.151
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X
Nat Microbiol (2022) 7 pp. 1635-1649 [ DOI: doi:10.1038/s41564-022-01235-4 Pubmed: 36151403 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s-gsas/6p spike trimer (Complex from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s-gsas/6p spike trimer bound to r1-32 fab with 3:1 ratio (Complex from Severe acute respiratory syndrome coronavirus 2)
- R1-32 fab (Complex)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
SARS-COV-2 Spike_GSAS_6P bound with two R1-32 Fabs
Resolution: 6.75 Å
EM Method: Single-particle
Fitted PDBs: 7ye5
Q-score: 0.029
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X
Nat Microbiol (2022) 7 pp. 1635-1649 [ Pubmed: 36151403 DOI: doi:10.1038/s41564-022-01235-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Sars-cov-2 s-gsas/6p spike trimer (Complex from Homo sapiens)
- Sars-cov-2 s-gsas/6p spike trimer bound with r1-32 fab with 3:2 ratio (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab (Complex)
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 7ye9
Q-score: 0.17
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X
Nat Microbiol (2022) 7 pp. 1635-1649 [ Pubmed: 36151403 DOI: doi:10.1038/s41564-022-01235-4 ]
- Sars-cov-2 spike_gsas_6p (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab (Complex)
- Sars-cov-2 spike_gsas_6p bound with three r1-32 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 7yeg
Q-score: 0.149
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X
Nat Microbiol (2022) 7 pp. 1635-1649 [ Pubmed: 36151403 DOI: doi:10.1038/s41564-022-01235-4 ]
- Sars-cov-2 spike_gsas_6p (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Ace2 (Complex from Homo sapiens)
- Sars-cov-2 spike_gsas_6p bound with three r1-32 fabs and three ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Light chain of r1-32 fab (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of r1-32 fab (23 kDa, Protein from Homo sapiens)
- Fabs (Complex)