Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8kci
Q-score: 0.356
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-bound hmrp5 outward-open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8wi0
Q-score: 0.482
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Wt-hmrp5 (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (2 kDa, Protein from Homo sapiens)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8wi3
Q-score: 0.431
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Hmrp5-nd inward-open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (164 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wi4
Q-score: 0.431
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Hmrp5-m6 inward open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8wi5
Q-score: 0.361
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ DOI: doi:10.1038/s41467-024-49204-1 Pubmed: 38844452 ]
- M5pi-bound hmrp5 (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (150 kDa, Protein from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (2 kDa, Protein from Homo sapiens)
Open human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8t50
Q-score: 0.385
Human HCN1 F186C S264C C309A bound to cAMP, reconstituted in LMNG + SPL
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8t4y
Q-score: 0.377
Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8h7l
Q-score: 0.377
Wang Y, Yan A, Song D, Duan M, Dong C, Chen J, Jiang Z, Gao Y, Rao M, Feng J, Zhang Z, Qi R, Ma X, Liu H, Yu B, Wang Q, Zong M, Jiao J, Xing P, Pan R, Li D, Xiao J, Sun J, Li Y, Zhang L, Shen Z, Sun B, Zhao Y, Zhang L, Dai J, Zhao J, Wang L, Dou C, Liu Z, Zhao J
Nat Commun (2024) 15 pp. 842-842 [ Pubmed: 38287016 DOI: doi:10.1038/s41467-024-45050-3 ]
- Ba7535 (Complex from Homo sapiens)
- Cryo-em structure of sars-cov-2 ba.2 spike protein in complex with ba7535 (Complex)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ba7535 fab heavt chain (49 kDa, Protein from Homo sapiens)
- Sars-cov-2 ba.2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Ba7535 fab light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 BA.2 RBD in complex with BA7535 fab (local refinement)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8h7z
Q-score: 0.461
Wang Y, Yan A, Song D, Duan M, Dong C, Chen J, Jiang Z, Gao Y, Rao M, Feng J, Zhang Z, Qi R, Ma X, Liu H, Yu B, Wang Q, Zong M, Jiao J, Xing P, Pan R, Li D, Xiao J, Sun J, Li Y, Zhang L, Shen Z, Sun B, Zhao Y, Zhang L, Dai J, Zhao J, Wang L, Dou C, Liu Z, Zhao J
Nat Commun (2024) 15 pp. 842-842 [ Pubmed: 38287016 DOI: doi:10.1038/s41467-024-45050-3 ]
- Ba7535 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 ba.2 rbd in complex with ba7535 fab (local refinement) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Ba7535 fab (49 kDa, Protein from Homo sapiens)