EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Chen J" AND xref_links:"alphafold" AND citation_journal_name:"CELL DISCOV" AND xref_links:"chebi"

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EMDB [4]

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EMD-36651

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hOCT1 in complex with metformin in outward open conformation

Release date: March 27, 2024
Resolution: 4.14 Å
EM Method: Single-particle
Fitted PDBs: 8jts
Q-score: 0.333

Zhang S, Zhu A, Kong F, Chen J, Lan B, He G, Gao K, Cheng L, Sun X, Yan C, Chen L, Liu X

Cell Discov (2024) 10 pp. 30-30 [ DOI: doi:10.1038/s41421-024-00664-1 Pubmed: 38485705 ]

Sample:

Solute carrier family 22 member 1 (62 kDa, Protein from Homo sapiens)
Metformin (129 Da, Ligand)
Human organic cation transporter in compelx wtih metformin in outward open conformation (Complex from Homo sapiens)

EMD-36652

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hOCT1 in complex with metformin in outward occluded conformation

Release date: March 27, 2024
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 8jtt
Q-score: 0.289

Zhang S, Zhu A, Kong F, Chen J, Lan B, He G, Gao K, Cheng L, Sun X, Yan C, Chen L, Liu X

Cell Discov (2024) 10 pp. 30-30 [ DOI: doi:10.1038/s41421-024-00664-1 Pubmed: 38485705 ]

Sample:

Human organic cation transporter in compelx wtih metformin in outward occluded conformation (Complex from Homo sapiens)
Metformin (129 Da, Ligand)
Solute carrier family 22 member 1 (58 kDa, Protein from Homo sapiens)

EMD-36653

Download Map 3D View

hOCT1 in complex with metformin in inward occluded conformation

Release date: March 27, 2024
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8jtv
Q-score: 0.346

Zhang S, Zhu A, Kong F, Chen J, Lan B, He G, Gao K, Cheng L, Sun X, Yan C, Chen L, Liu X

Cell Discov (2024) 10 pp. 30-30 [ Pubmed: 38485705 DOI: doi:10.1038/s41421-024-00664-1 ]

Sample:

Human organic cation transporter in compelx wtih metformin in inward occludded conformation (Complex from Homo sapiens)
Metformin (129 Da, Ligand)
Solute carrier family 22 member 1 (62 kDa, Protein from Homo sapiens)

EMD-36658

Download Map 3D View

hOCT1 in complex with spironolactone in inward facing occluded conformation

Release date: March 27, 2024
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8ju0
Q-score: 0.503

Zhang S, Zhu A, Kong F, Chen J, Lan B, He G, Gao K, Cheng L, Sun X, Yan C, Chen L, Liu X

Cell Discov (2024) 10 pp. 30-30 [ DOI: doi:10.1038/s41421-024-00664-1 Pubmed: 38485705 ]

Sample:

Spironolactone (416 Da, Ligand)
Human organic cation transporter in compelx wtih spironolactone in inward facing occludded conformation (Complex from Homo sapiens)
Solute carrier family 22 member 1 (62 kDa, Protein from Homo sapiens)

Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

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