Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8w0a
Q-score: 0.435
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*t)-3') (13 kDa, DNA from Homo sapiens)
- Human dna polymerase theta helicase domain in complex with ssdna (253 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9asj
Q-score: 0.411
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Human dna polymerase theta helicase domain in complex with inhibitor amp-pnp (199 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain dimer, apo-form
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9ask
Q-score: 0.389
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
- Human dna polymerase theta helicase domain dimer, apo-form (199 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain tetramer, apo-form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9asl
Q-score: 0.392
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
- Human dna polymerase theta helicase domain tetramer, apo-form (398 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain in microhomology annealed state 1, dimer form
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9c5q
Q-score: 0.479
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ Pubmed: 38895274 DOI: doi:10.1101/2024.06.07.597860 ]
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8ud2
Q-score: 0.672
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8ud3
Q-score: 0.605
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Homohexamer of nsp15 in complex with poly(a/u) rna (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ud4
Q-score: 0.511
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with rna duplex (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ud5
Q-score: 0.541
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with rna duplex (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)