BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP Polyclonal Antibody FP4
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost 2 in complex with NHP antibody V1V2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost 2 in complex with NHP Polyclonal Antibody N625
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody Base1
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
Boost 2 SOSIP.664 in complex with NHP polyclonal antibody Base2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ DOI: doi:10.1101/2023.06.26.545779 Pubmed: 37425865 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody Base3
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ DOI: doi:10.1101/2023.06.26.545779 Pubmed: 37425865 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8sw7
Q-score: 0.444
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ DOI: doi:10.1101/2023.06.26.545779 Pubmed: 37425865 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 boost 2 in complex with nhp polyclonal antibody fp1 (470 kDa, Complex from Human immunodeficiency virus 1)
- Fp1 light chain (9 kDa, Protein from Macaca mulatta)
- Bg505 boost 2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 boost 2 gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- Fp1 heavy chain (10 kDa, Protein from Macaca mulatta)
Negative stain EM map of BG505 SOSIP in complex with Rh4O9.8 monoclonal antibody (as Fab fragment)
Antanasijevic A, Bowman CA, Kirchdoerfer RN, Cottrell CA, Ozorowski G, Upadhyay AA, Cirelli KM, Carnathan DG, Enemuo CA, Sewall LM, Nogal B, Zhao F, Groschel B, Schief WR, Sok D, Silvestri G, Crotty S, Bosinger SE, Ward AB
Sci Adv (2022) 8 pp. eabk2039-eabk2039 [ Pubmed: 35044813 DOI: doi:10.1126/sciadv.abk2039 ]
BG505 SOSIP.v5.2 in complex with the polyclonal Fab pAbC-1 from animal Rh.4O9
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7mdt
Q-score: 0.481
Antanasijevic A, Bowman CA, Kirchdoerfer RN, Cottrell CA, Ozorowski G, Upadhyay AA, Cirelli KM, Carnathan DG, Enemuo CA, Sewall LM, Nogal B, Zhao F, Groschel B, Schief WR, Sok D, Silvestri G, Crotty S, Bosinger SE, Ward AB
Sci Adv (2022) 8 pp. eabk2039-eabk2039 [ DOI: doi:10.1126/sciadv.abk2039 Pubmed: 35044813 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Surface protein gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
- Rh4o9.8 monoclonal antibody light chain (11 kDa, Protein from Macaca mulatta)
- Bg505 sosip.v5.2 in complex with the polyclonal fab sample isolated from animal rh4o9. (Complex from Human immunodeficiency virus)
- Rh4o9.8 monoclonal antibody heavy chain (12 kDa, Protein from Macaca mulatta)