BA.2(S375) Spike (S6P)/hACE2 complex
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8wgv
Q-score: 0.376
He X, Zhang X, Wu B, Deng J, Zhang Y, Zhu A, Yuan Y, Lin Y, Chen A, Feng J, Wang X, Wu S, Liu Y, Liu J, Wang Y, Li R, Liang C, Yuan Q, Liang Y, Fang Q, Xi Z, Li W, Liang L, Zhang Z, Tang H, Peng Y, Ke C, Ma X, Cai W, Pan T, Liu B, Deng K, Chen J, Zhao J, Wei X, Chen R, Zhang Y, Zhang H
Nat Immunol (2024) 25 pp. 622-632 [ Pubmed: 38454157 DOI: doi:10.1038/s41590-024-01776-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ba.2(s375) spike (s6p)/hace2 complex (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wgw
Q-score: 0.541
He X, Zhang X, Wu B, Deng J, Zhang Y, Zhu A, Yuan Y, Lin Y, Chen A, Feng J, Wang X, Wu S, Liu Y, Liu J, Wang Y, Li R, Liang C, Yuan Q, Liang Y, Fang Q, Xi Z, Li W, Liang L, Zhang Z, Tang H, Peng Y, Ke C, Ma X, Cai W, Pan T, Liu B, Deng K, Chen J, Zhao J, Wei X, Chen R, Zhang Y, Zhang H
Nat Immunol (2024) 25 pp. 622-632 [ DOI: doi:10.1038/s41590-024-01776-2 Pubmed: 38454157 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (70 kDa, Protein from Homo sapiens)
- Rbd complexed with human ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of the C26-CoA-bound Lac1-Lip1 complex
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8izd
Q-score: 0.562
Xie T, Fang Q, Zhang Z, Wang Y, Dong F, Gong X
EMBO J (2023) 42 pp. e114889-e114889 [ DOI: doi:10.15252/embj.2023114889 Pubmed: 37953642 ]
- Lac1-lip1 complex (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Hexacosanoyl-coa (1 kDa, Ligand)
- Ceramide synthase subunit lip1 (17 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ceramide synthase lac1 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Cryo-EM structure of the Lac1-Lip1 (Lip1-S74F) complex
Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 8izf
Q-score: 0.396
Xie T, Fang Q, Zhang Z, Wang Y, Dong F, Gong X
EMBO J (2023) 42 pp. e114889-e114889 [ Pubmed: 37953642 DOI: doi:10.15252/embj.2023114889 ]
- Lac1-lip1 (lip1-s74f) complex (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ceramide synthase subunit lip1 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ceramide synthase lac1 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with 8H12
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with 3E2
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8iv4
Q-score: 0.506
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
- Nabs 8h12 and 3e2 (Complex from Mus musculus)
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8iv5
Q-score: 0.494
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nabs 8h12,1c4 (Complex from Mus musculus)
- Light chain of 1c4 (11 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 spike protein in complex with 8h12 (Complex)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 1c4 (13 kDa, Protein from Mus musculus)