Cryo-EM structure of ComA bound to its mature substrate CSP peptide
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8k4b
Q-score: 0.297
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ Pubmed: 37935699 DOI: doi:10.1038/s41467-023-42852-9 ]
- Zinc ion (65 Da, Ligand)
- Coma (Complex from Streptococcus pneumoniae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Competence factor transporting atp-binding protein/permease coma (80 kDa, Protein from Streptococcus pneumoniae D39)
Cryo-EM structure of nucleotide-bound ComA E647Q mutant with Mg2+
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8k7a
Q-score: 0.235
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ Pubmed: 37935699 DOI: doi:10.1038/s41467-023-42852-9 ]
- Magnesium ion (24 Da, Ligand)
- Transport/processing atp-binding protein coma (80 kDa, Protein from Streptococcus pneumoniae R6)
- Coma (Complex from Streptococcus pneumoniae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8hf5
Q-score: 0.501
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ Pubmed: 37935699 DOI: doi:10.1038/s41467-023-42852-9 ]
- Magnesium ion (24 Da, Ligand)
- Transport/processing atp-binding protein coma (80 kDa, Protein from Streptococcus pneumoniae D39)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Coma (Complex from Streptococcus pneumoniae D39)
Aplysia californica FaNaC in ligand bound state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7yvb
Q-score: 0.539
Liu F, Dang Y, Li L, Feng H, Li J, Wang H, Zhang X, Zhang Z, Ye S, Tian Y, Chen Q
Nat Chem Biol (2023) 19 pp. 1276-1285 [ DOI: doi:10.1038/s41589-023-01401-7 Pubmed: 37550431 ]
- Fmrfamide-gated na+ channel (76 kDa, Protein from Aplysia californica)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Phe-met-arg-phe-amide (599 Da, Protein from synthetic construct)
- Trimeric fmrfamide activated sodium channel from aplysia californica (acfanac) (73 kDa, Complex from Aplysia californica)
Aplysia californica FaNaC in apo state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7yvc
Q-score: 0.532
Liu F, Dang Y, Li L, Feng H, Li J, Wang H, Zhang X, Zhang Z, Ye S, Tian Y, Chen Q
Nat Chem Biol (2023) 19 pp. 1276-1285 [ Pubmed: 37550431 DOI: doi:10.1038/s41589-023-01401-7 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Trimeric fmrfamide activated sodium channel from aplysia californica (acfanac) (73 kDa, Complex from Aplysia californica)
- Calcium ion (40 Da, Ligand)
- Fmrfamide-gated na+ channel (76 kDa, Protein from Aplysia californica)
local structure of hu33 and spike
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7wb5
Q-score: 0.471
Duan X, Shi R, Liu P, Huang Q, Wang F, Chen X, Feng H, Huang W, Xiao J, Yan J
Signal Transduct Target Ther (2022) 7 pp. 23-23 [ Pubmed: 35078968 DOI: doi:10.1038/s41392-022-00879-2 ]
- Hu33 heavy chain (13 kDa, Protein from Homo sapiens)
- Surface glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Hu33 light chain (11 kDa, Protein from Homo sapiens)
- Local structure of r33 and rbd (Complex from Homo sapiens)