Local refinement map of TFIIIC TauB-DNA monomer
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cli
Q-score: 0.492
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ DOI: doi:10.1126/sciadv.adh2019 Pubmed: 37418517 ]
- Tfiiic taub-dna monomer (300 kDa, Complex from Homo sapiens)
- Dna (35-mer) (10 kDa, DNA from Homo sapiens)
- Dna (35-mer) (10 kDa, DNA from Homo sapiens)
- General transcription factor 3c polypeptide 2 (102 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 4 (92 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- General transcription factor 3c polypeptide 1 (244 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8clj
Q-score: 0.49
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ DOI: doi:10.1126/sciadv.adh2019 Pubmed: 37418517 ]
- Tfiiic taub-dna dimer (600 kDa, Complex from Homo sapiens)
- Tdna (35-mer) (10 kDa, DNA from Homo sapiens)
- Tdna (35-mer) (10 kDa, DNA from Homo sapiens)
- General transcription factor 3c polypeptide 2 (102 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 4 (92 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- General transcription factor 3c polypeptide 1 (244 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8clk
Q-score: 0.358
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ DOI: doi:10.1126/sciadv.adh2019 Pubmed: 37418517 ]
- General transcription factor 3c polypeptide 3 (101 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 5 (61 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 6 (24 kDa, Protein from Homo sapiens)
- Tfiiic taua subcomplex (330 kDa, Complex from Homo sapiens)
- General transcription factor 3c polypeptide 1 (244 kDa, Protein from Homo sapiens)
TFIIIC TauA complex map (sample without DNA)
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ Pubmed: 37418517 DOI: doi:10.1126/sciadv.adh2019 ]
- Tfiiic taua subcomplex (330 kDa, Complex from Homo sapiens)
Structural insights into human TFIIIC promoter recognition
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8cll
Q-score: 0.445
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ Pubmed: 37418517 DOI: doi:10.1126/sciadv.adh2019 ]
- General transcription factor 3c polypeptide 2 (102 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 4 (92 kDa, Protein from Homo sapiens)
- General transcription factor 3c polypeptide 1 (244 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Tfiiic taub dimer (560 kDa, Complex from Homo sapiens)
Consensus map of TauB-DNA dimer (Nu-refinement)
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ Pubmed: 37418517 DOI: doi:10.1126/sciadv.adh2019 ]
- Tfiiic taub-dna dimer (600 kDa, Complex from Homo sapiens)
Local refinement map of TFIIIC TauB-DNA monomer 2
Seifert-Davila W, Girbig M, Hauptmann L, Hoffmann T, Eustermann S, Muller CW
Sci Adv (2023) 9 pp. eadh2019-eadh2019 [ Pubmed: 37418517 DOI: doi:10.1126/sciadv.adh2019 ]
- Tfiiic taub-dna monomer 2 (600 kDa, Complex from Homo sapiens)
Cryo-EM structure of human RNA Polymerase I in elongation state
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7ob9
Q-score: 0.519
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ Pubmed: 34887565 DOI: doi:10.1038/s41594-021-00693-4 ]
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
- Dna non-template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Rna (9 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Rna polymerase i (Complex)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna template strand (13 kDa, DNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Rna and dna (Complex from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)
Cryo-EM structure of human RNA Polymerase I in complex with RRN3
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7oba
Q-score: 0.435
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ Pubmed: 34887565 DOI: doi:10.1038/s41594-021-00693-4 ]
- Rna polymerase i in complex with rrn3 (670 kDa, Complex)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Rna polymerase i-specific transcription initiation factor rrn3 (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Rna polymerase i-specific transcription initiation factor rrn3 (74 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
Cryo-EM structure of human RNA Polymerase I Open Complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7obb
Q-score: 0.401
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ Pubmed: 34887565 DOI: doi:10.1038/s41594-021-00693-4 ]
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Rna polymerase i open complex (600 kDa, Complex)
- Dna (Complex from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
- Dna non-template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)