Wei G, Iqbal N, Courouble VV, Francis AC, Singh PK, Hudait A, Annamalai AS, Bester S, Huang SW, Shkriabai N, Briganti L, Haney R, KewalRamani VN, Voth GA, Engelman AN, Melikyan GB, Griffin PR, Asturias F, Kvaratskhelia M
Nat Commun (2022) 13 pp. 5879-5879 [ DOI: doi:10.1038/s41467-022-33662-6 Pubmed: 36202818 ]
Wei G, Iqbal N, Courouble VV, Francis AC, Singh PK, Hudait A, Annamalai AS, Bester S, Huang SW, Shkriabai N, Briganti L, Haney R, KewalRamani VN, Voth GA, Engelman AN, Melikyan GB, Griffin PR, Asturias F, Kvaratskhelia M
Nat Commun (2022) 13 pp. 5879-5879 [ DOI: doi:10.1038/s41467-022-33662-6 Pubmed: 36202818 ]
Wei G, Iqbal N, Courouble VV, Francis AC, Singh PK, Hudait A, Annamalai AS, Bester S, Huang SW, Shkriabai N, Briganti L, Haney R, KewalRamani VN, Voth GA, Engelman AN, Melikyan GB, Griffin PR, Asturias F, Kvaratskhelia M
Nat Commun (2022) 13 pp. 5879-5879 [ DOI: doi:10.1038/s41467-022-33662-6 Pubmed: 36202818 ]
Human mitochondrial LONP1 in complex with Bortezomib
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7krz
Q-score: 0.572
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ Pubmed: 34050165 DOI: doi:10.1038/s41467-021-23495-0 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Lon protease homolog, mitochondrial (59 kDa, Protein from Homo sapiens)
- Endogenous co-purified substrate (1 kDa, Protein from Escherichia coli BL21(DE3))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Human mitochondrial lonp1 in complex with bortezomib (462 kDa, Complex from Homo sapiens)
- N-[(1r)-1-(dihydroxyboryl)-3-methylbutyl]-n-(pyrazin-2-ylcarbonyl)-l-phenylalaninamide (384 Da, Ligand)
WalkerB mutant human mitochondrial LONP1 bound to endogenous substrate
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ Pubmed: 34050165 DOI: doi:10.1038/s41467-021-23495-0 ]
Substrate-free human mitochondrial LONP1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ksl
Q-score: 0.506
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ Pubmed: 34050165 DOI: doi:10.1038/s41467-021-23495-0 ]
- Substrate-free human mitochondrial lonp1 (462 kDa, Complex from Homo sapiens)
- Lon protease homolog, mitochondrial (58 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Human mitochondrial LONP1 with endogenous substrate
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ksm
Q-score: 0.568
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ Pubmed: 34050165 DOI: doi:10.1038/s41467-021-23495-0 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Unidentified endogenous substrate (1 kDa, Protein from Escherichia coli BL21(DE3))
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Lon protease homolog, mitochondrial (59 kDa, Protein from Homo sapiens)
- Human mitochondrial lonp1 with endogenous substrate (462 kDa, Complex from Homo sapiens)
Negative stain (RCT) surface of full-length glucagon receptor FAB complex
Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H
Nat Commun (2015) 6 pp. 7859-7859 [ Pubmed: 26227798 DOI: doi:10.1038/ncomms8859 ]
Negative stain (RCT) surface of full-length glucagon receptor FAB complex
Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H
Nat Commun (2015) 6 pp. 7859-7859 [ Pubmed: 26227798 DOI: doi:10.1038/ncomms8859 ]