Copper-transporting ATPase HMA4 in E1 state apo
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8q73
Q-score: 0.259
Guo Z, Oradd F, Bagenholm V, Gronberg C, Ma JF, Ott P, Wang Y, Andersson M, Pedersen PA, Wang K, Gourdon P
Nat Commun (2024) 15 pp. 2690-2690 [ Pubmed: 38538615 DOI: doi:10.1038/s41467-024-47001-4 ]
Copper-transporting ATPase HMA4 in E1 state with Cu
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8q74
Q-score: 0.282
Guo Z, Oradd F, Bagenholm V, Gronberg C, Ma JF, Ott P, Wang Y, Andersson M, Pedersen PA, Wang K, Gourdon P
Nat Commun (2024) 15 pp. 2690-2690 [ Pubmed: 38538615 DOI: doi:10.1038/s41467-024-47001-4 ]
Copper-transporting ATPase HMA4 in E2P state with BeF
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8q76
Q-score: 0.33
Guo Z, Oradd F, Bagenholm V, Gronberg C, Ma JF, Ott P, Wang Y, Andersson M, Pedersen PA, Wang K, Gourdon P
Nat Commun (2024) 15 pp. 2690-2690 [ Pubmed: 38538615 DOI: doi:10.1038/s41467-024-47001-4 ]
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yrd
Q-score: 0.484
Huang L, Wang Y, Long H, Zhu H, Wen Z, Zhang L, Zhang W, Guo Z, Wang L, Tang F, Hu J, Bao K, Zhu P, Li G, Zhou Z
Mol Cell (2023) 83 pp. 2884-2895.e7 [ Pubmed: 37536340 DOI: doi:10.1016/j.molcel.2023.07.001 ]
- Histone h2b 1.1 (10 kDa, Protein from Xenopus laevis)
- Histone h2a.z (12 kDa, Protein from Homo sapiens)
- S-adenosylmethionine (398 Da, Ligand)
- [histone h4]-n-methyl-l-lysine20 n-methyltransferase kmt5b (32 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (45 kDa, DNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Histone methyltransferase and nucleosome complex (Complex from Homo sapiens)
- Histone h3.2 (12 kDa, Protein from Xenopus laevis)
The BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8hii
Q-score: 0.338
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- The bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hij
Q-score: 0.296
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- The 5-mthf-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- N-[4-({[(6s)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-l-glutamic acid (459 Da, Ligand)
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8hik
Q-score: 0.249
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- Thiamine diphosphate (425 Da, Ligand)
- The tpp-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
cryo-EM structure of human H2A.Z.2.2 nucleosome
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6m4d
Q-score: 0.311
Zhou M, Dai L, Li C, Shi L, Huang Y, Guo Z, Wu F, Zhu P, Zhou Z
EMBO J (2021) 40 pp. e105907-e105907 [ DOI: doi:10.15252/embj.2020105907 Pubmed: 33073403 ]
- Dna (125-mer) (45 kDa, DNA from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- H2a.z.2.2 nucleosome (Complex from Homo sapiens)
- Dna (125-mer) (45 kDa, DNA from Homo sapiens)
- Histone h2a.v (12 kDa, Protein from Homo sapiens)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
cryo-EM structure of human H2A.B nucleosome
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6m4g
Q-score: 0.493
Zhou M, Dai L, Li C, Shi L, Huang Y, Guo Z, Wu F, Zhu P, Zhou Z
EMBO J (2021) 40 pp. e105907-e105907 [ DOI: doi:10.15252/embj.2020105907 Pubmed: 33073403 ]
- H2a.b nucleosome (Complex from Homo sapiens)
- Dna (93-mer) (45 kDa, DNA from Homo sapiens)
- Dna (93-mer) (45 kDa, DNA from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
- Histone h2a-bbd type 2/3 (12 kDa, Protein from Homo sapiens)
Structural mechanism of nucleosome dynamics governed by histone H2A variants H2A.B or H2A.Z.2.2
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6m4h
Q-score: 0.365
Zhou M, Dai L, Li C, Shi L, Huang Y, Guo Z, Wu F, Zhu P, Zhou Z
EMBO J (2021) 40 pp. e105907-e105907 [ DOI: doi:10.15252/embj.2020105907 Pubmed: 33073403 ]
- Dna (103-mer) (45 kDa, DNA from Homo sapiens)
- H2a.b nucleosome (Complex from Homo sapiens)
- Dna (103-mer) (45 kDa, DNA from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
- Histone h2a-bbd type 2/3 (12 kDa, Protein from Homo sapiens)