The BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8hii
Q-score: 0.338
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- The bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hij
Q-score: 0.296
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- The 5-mthf-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- N-[4-({[(6s)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-l-glutamic acid (459 Da, Ligand)
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8hik
Q-score: 0.249
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ DOI: doi:10.1038/s41421-022-00508-w Pubmed: 36575193 ]
- Thiamine diphosphate (425 Da, Ligand)
- The tpp-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
Fiber-forming RubisCO derived from ancestral sequence reconstruction and rational engineering
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7qvi
Q-score: 0.571
Schulz L, Guo Z, Zarzycki J, Steinchen W, Schuller JM, Heimerl T, Prinz S, Mueller-Cajar O, Erb TJ, Hochberg GKA
Science (2022) 378 pp. 155-160 [ DOI: doi:10.1126/science.abq1416 Pubmed: 36227987 ]
- Rubisco large subunit (51 kDa, Protein from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- 2-carboxyarabinitol-1,5-diphosphate (356 Da, Ligand)
- Ancestral sequence reconstruction of rubisco large subunit in complex with cabp and magnesium (873 kDa, Complex from synthetic construct)