Lassa GPC Trimer in complex with Fab 8.11G and nanobody D5
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 8t5c
Q-score: 0.301
Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD
Nat Commun (2024) 15 pp. 285-285 [ Pubmed: 38177144 DOI: doi:10.1038/s41467-023-44534-y ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 8.11g light chain (12 kDa, Protein from Homo sapiens)
- 8.11g heavy chain (13 kDa, Protein from Homo sapiens)
- D5 nanobody (13 kDa, Protein from Camelus bactrianus)
- Glycoprotein g1 (22 kDa, Protein from Lassa virus Josiah)
- Glycoprotein g2 (22 kDa, Protein from Lassa virus Josiah)
- Lassa gpc trimer in complex with fab 8.11g and nanobody d5 (Complex from Lassa virus Josiah)
Lassa GPC trimer in complex with Fab GP23
Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD
Nat Commun (2024) 15 pp. 285-285 [ Pubmed: 38177144 DOI: doi:10.1038/s41467-023-44534-y ]
Ligand-free Lassa GPC Trimer with C3 Symmetry
Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD
Nat Commun (2024) 15 pp. 285-285 [ Pubmed: 38177144 DOI: doi:10.1038/s41467-023-44534-y ]
- Lassa gpc (Protein from Lassa virus Josiah)
- Lassa gpc trimer (Complex from Lassa virus Josiah)
Ligand-free Lassa GPC Trimer with C1 Symmetry
Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD
Nat Commun (2024) 15 pp. 285-285 [ Pubmed: 38177144 DOI: doi:10.1038/s41467-023-44534-y ]
Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 7tpr
Q-score: 0.407
Hong J, Kwon HJ, Cachau R, Chen CZ, Dandey VP, Martin N, Esposito D, Ortega-Rodriguez U, Xu M, Borgnia MJ, Xie H, Ho M
bioRxiv (2021) [ DOI: doi:10.1101/2021.10.27.465996 Pubmed: 34751270 ]
- Ternary complex of sars-cov-2 spike protein ectodomain (wuhan strain) and camel nanobodies 7a3 and 8a2. (17 kDa, Complex)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Camel nanobody 7a3 (Complex from Camelus dromedarius)
- Camel nanobody 8a2 (Complex from Camelus dromedarius)
- Nanobody 7a3 (13 kDa, Protein from Camelus dromedarius)
- Spike glycoprotein (126 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Nanobody 8a2 (13 kDa, Protein from Camelus dromedarius)
Resolution: 21.0 Å
EM Method: Single-particle
Fitted PDBs: 7t62
Q-score: 0.055
Li N, Torres MB, Spetz MR, Wang R, Peng L, Tian M, Dower CM, Nguyen R, Sun M, Tai CH, de Val N, Cachau R, Wu X, Hewitt SM, Kaplan RN, Khan J, St Croix B, Thiele CJ, Ho M
Cell Rep Med (2021) 2 pp. 100297-100297 [ DOI: doi:10.1016/j.xcrm.2021.100297 Pubmed: 34195677 ]
- Gpc2 het ct3 complex (Complex)
- Glypican-2 (61 kDa, Protein from Homo sapiens)
- Ct3 (47 kDa, Protein from Mus musculus)
