FoxP3 tetramer on TTTG repeats
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8sro
Q-score: 0.455
Zhang W, Leng F, Wang X, Ramirez RN, Park J, Benoist C, Hur S
Nature (2023) 624 pp. 433-441 [ Pubmed: 38030726 DOI: doi:10.1038/s41586-023-06793-z ]
- Foxp3-dna complex (Complex from Mus musculus)
- Dna 72-mer (22 kDa, DNA from synthetic construct)
- Forkhead box protein p3 (27 kDa, Protein from Mus musculus)
- Dna 72-mer (22 kDa, DNA from synthetic construct)
FoxP3 forms Ladder-like multimer to bridge TTTG repeats
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8srp
Q-score: 0.335
Zhang W, Leng F, Wang X, Ramirez RN, Park J, Benoist C, Hur S
Nature (2023) 624 pp. 433-441 [ Pubmed: 38030726 DOI: doi:10.1038/s41586-023-06793-z ]
- Foxp3-dna complex (Complex from Mus musculus)
- Dna 72-mer (22 kDa, DNA from synthetic construct)
- Forkhead box protein p3 (27 kDa, Protein from Mus musculus)
- Dna 72-mer (22 kDa, DNA from synthetic construct)
Cryo-EM structure of MDA5-dsRNA in complex with TRIM65 PSpry domain (Monomer)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7jl0
Q-score: 0.395
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Interferon-induced helicase c domain-containing protein 1 (84 kDa, Protein from Homo sapiens)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Tripartite motif-containing protein 65 (21 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*cp*ap*gp*up*cp*ap*gp*up*cp*ap*gp*up*c)-3') (4 kDa, RNA from Homo sapiens)
- Ternary complex of mda5:dsrna:trim65 (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Rna (5'-r(p*gp*ap*cp*up*gp*ap*cp*up*gp*ap*cp*up*gp*a)-3') (4 kDa, RNA from Homo sapiens)
Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7jl1
Q-score: 0.489
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Ternary complex of rig-i:dsrna:riplet pryspry (Complex from Homo sapiens)
- Dsrna strand 2 (4 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- E3 ubiquitin-protein ligase rnf135 (21 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Dsrna strand 1 (4 kDa, RNA from Homo sapiens)
- Antiviral innate immune response receptor rig-i (82 kDa, Protein from Homo sapiens)
Cryo-EM structure of MDA5-dsRNA filament in complex with TRIM65 PSpry domain (Trimer)
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7jl2
Q-score: 0.362
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Rna (44-mer) (13 kDa, RNA from Homo sapiens)
- Tripartite motif-containing protein 65 (21 kDa, Protein from Homo sapiens)
- Rna (44-mer) (14 kDa, RNA from Homo sapiens)
- Interferon-induced helicase c domain-containing protein 1 (84 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ternary complex of mda5-dsrna-trim65 (Complex from Homo sapiens)
Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer)
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 7jl3
Q-score: 0.296
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dsrna strand 2 (13 kDa, RNA from Homo sapiens)
- Dsrna strand1 (13 kDa, RNA from Homo sapiens)
- Antiviral innate immune response receptor rig-i (82 kDa, Protein from Homo sapiens)
- Ternary complex of dsrna-bound rig-i filament with riplet pryspry domain (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rnf135 (21 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
3.6 Angstrom resolution MAVS filament generated from helical reconstruction
Wu B, Peisley A, Tetrault D, Li Z, Egelman EH, Magor KE, Walz T, Penczek PA, Hur S
Mol Cell (2014) 55 pp. 511-523 [ Pubmed: 25018021 DOI: doi:10.1016/j.molcel.2014.06.010 ]
3.6 Angstrom resolution MAVS filament generated from helical reconstruction, truncated map
Resolution: 3.64 Å
EM Method: Helical reconstruction
Fitted PDBs: 3j6j
Q-score: 0.354
Wu B, Peisley A, Tetrault D, Li Z, Egelman EH, Magor KE, Walz T, Penczek PA, Hur S
Mol Cell (2014) 55 pp. 511-523 [ DOI: doi:10.1016/j.molcel.2014.06.010 Pubmed: 25018021 ]