Cryo-EM structure of the human SAGA complex
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8h7g
Q-score: 0.273
Zhang Y, Yin C, Yin Y, Wei M, Jing W, Peng C, Chen Z, Huang J
Cell Discov (2022) 8 pp. 125-125 [ DOI: doi:10.1038/s41421-022-00489-w Pubmed: 36414614 ]
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from human)
- Transcription initiation protein spt3 homolog (35 kDa, Protein from human)
- Unassigned sequence (1 kDa, Protein from human)
- Splicing factor 3b subunit 3 (135 kDa, Protein from human)
- Transcription factor spt20 homolog (85 kDa, Protein from human)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from human)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from human)
- Transformation/transcription domain-associated protein (438 kDa, Protein from human)
- Splicing factor 3b subunit 5 (10 kDa, Protein from human)
- Staga complex 65 subunit gamma (50 kDa, Protein from Homo sapiens)
- Human saga transcriptional coactivator complex (1 MDa, Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from human)
- Ataxin-7 (95 kDa, Protein from human)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (67 kDa, Protein from human)
- Transcriptional adapter 1 (41 kDa, Protein from Homo sapiens)
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6j99
Q-score: 0.132
Yao T, Jing W, Hu Z, Tan M, Cao M, Wang Q, Li Y, Yuan G, Lei M, Huang J
Cell Res (2019) 29 pp. 330-333 [ DOI: doi:10.1038/s41422-019-0146-7 Pubmed: 30770869 ]
- Human dot1l in complex with an h2b-monoubiquitinated nucleosome (Complex)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Histone h2a (14 kDa, Protein from Xenopus laevis)
- Dna (145-mer) (45 kDa, DNA from synthetic construct)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Histone-lysine n-methyltransferase, h3 lysine-79 specific (47 kDa, Protein from Homo sapiens)
- Dna (144-mer) (45 kDa, DNA from synthetic construct)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Human dot1l in complex with an h2b-monoubiquitinated nucleosome (Complex from Human)
- Human dot1l in complex with an h2b-monoubiquitinated nucleosome (250 kDa, Complex from African clawed frog)
Cryo-EM structure of human DOT1L in complex with nucleosome
Yao T, Jing W, Hu Z, Tan M, Cao M, Wang Q, Li Y, Yuan G, Lei M, Huang J
Cell Res (2019) 29 pp. 330-333 [ DOI: doi:10.1038/s41422-019-0146-7 Pubmed: 30770869 ]
- Human dot1l in complex with nucleosome (240 kDa, Complex from Homo sapiens)