SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7f3q
Q-score: 0.482
Dou Y, Xu K, Deng YQ, Jia Z, Lan J, Xu X, Zhang G, Cao T, Liu P, Wang X, Wang X, Xu L, Du P, Qin CF, Liu H, Li Y, Wu G, Wang K, Lu B
Antib Ther (2023) 6 pp. 76-86 [ Pubmed: 37077472 DOI: doi:10.1093/abt/tbad002 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of a34-2 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s protein rbd in complex with two fabs (Complex)
- Light chain of a5-10 fab (22 kDa, Protein from Homo sapiens)
- Fab (Complex from Homo sapiens)
- Sars-cov-2 s protein rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of a34-2 fab (22 kDa, Protein from Homo sapiens)
- Heavy chain of a5-10 fab (24 kDa, Protein from Homo sapiens)
- 2-(n-morpholino)-ethanesulfonic acid (195 Da, Ligand)
Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7dqa
Q-score: 0.508
Liu N, Zheng LM, Xu J, Wang J, Hu CX, Lan J, Zhang X, Zhang JC, Xu K, Cheng H, Yang Z, Gao X, Wang XQ, Peng HL, Chen YN, Wang HW
Biophys Rep (2022) 7 pp. 227-238 [ DOI: doi:10.52601/bpr.2021.210007 ]
- Cryo-em structure of sars-cov2 rbd-ace2 complex (95 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Chloride ion (35 Da, Ligand)
- Water (18 Da, Ligand)
- Spike glycoprotein (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Sars-cov2 rbd (Complex)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
S protein of SARS-CoV-2 in complex bound with P36-5D2(state2)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7fae
Q-score: 0.292
Shan S, Mok CK, Zhang S, Lan J, Li J, Yang Z, Wang R, Cheng L, Fang M, Aw ZQ, Yu J, Zhang Q, Shi X, Zhang T, Zhang Z, Wang J, Wang X, Chu JJH, Zhang L
Front Immunol (2021) 12 pp. 766821-766821 [ DOI: doi:10.3389/fimmu.2021.766821 Pubmed: 34966387 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- P36-5d2 antibody fab (Complex)
- P36-5d2 heavy chain (51 kDa, Protein from Homo sapiens)
- S protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S protein of sars-cov-2 in complex bound with p36-5d2 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 light chain (25 kDa, Protein from Homo sapiens)
S protein of SARS-CoV-2 in complex bound with P36-5D2 (state1)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7faf
Q-score: 0.258
Shan S, Mok CK, Zhang S, Lan J, Li J, Yang Z, Wang R, Cheng L, Fang M, Aw ZQ, Yu J, Zhang Q, Shi X, Zhang T, Zhang Z, Wang J, Wang X, Chu JJH, Zhang L
Front Immunol (2021) 12 pp. 766821-766821 [ DOI: doi:10.3389/fimmu.2021.766821 Pubmed: 34966387 ]
- P36-5d2 fab (Complex)
- P36-5d2 heavy chain (51 kDa, Protein from Homo sapiens)
- S protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S protein of sars-cov-2 in complex bound with p36-5d2 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- P36-5d2 light chain (25 kDa, Protein from Homo sapiens)
SARS-COV-2 Spike RBDMACSp6 binding to hACE2
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7fdg
Q-score: 0.364
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF
Nat Commun (2021) 12 pp. 5654-5654 [ Pubmed: 34580297 DOI: doi:10.1038/s41467-021-25903-x ]
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (24 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike rbdmacsp6-hace2 complex (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-COV-2 Spike RBDMACSp25 binding to hACE2
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 7fdh
Q-score: 0.433
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF
Nat Commun (2021) 12 pp. 5654-5654 [ Pubmed: 34580297 DOI: doi:10.1038/s41467-021-25903-x ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike rbdmacsp25-hace2 complex (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Homo sapiens)
- Spike protein s1 (24 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-COV-2 Spike RBDMACSp36 binding to mACE2
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7fdk
Q-score: 0.442
Sun S, Gu H, Cao L, Chen Q, Ye Q, Yang G, Li RT, Fan H, Deng YQ, Song X, Qi Y, Li M, Lan J, Feng R, Guo Y, Zhu N, Qin S, Wang L, Zhang YF, Zhou C, Zhao L, Chen Y, Shen M, Cui Y, Yang X, Wang X, Tan W, Wang H, Wang X, Qin CF
Nat Commun (2021) 12 pp. 5654-5654 [ Pubmed: 34580297 DOI: doi:10.1038/s41467-021-25903-x ]
- Sars-cov-2 spike rbdmacsp36-mace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (24 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (71 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of bat RaTG13 spike glycoprotein
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7cn4
Q-score: 0.544
Zhang S, Qiao S, Yu J, Zeng J, Shan S, Tian L, Lan J, Zhang L, Wang X
Nat Commun (2021) 12 pp. 1607-1607 [ Pubmed: 33707453 DOI: doi:10.1038/s41467-021-21767-3 ]
- Spike glycoprotein (140 kDa, Protein from Bat coronavirus RaTG13)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ratg13 glycoprotein (Complex from Bat coronavirus RaTG13)
Cryo-EM structure of PCoV_GX spike glycoprotein
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7cn8
Q-score: 0.56
Zhang S, Qiao S, Yu J, Zeng J, Shan S, Tian L, Lan J, Zhang L, Wang X
Nat Commun (2021) 12 pp. 1607-1607 [ Pubmed: 33707453 DOI: doi:10.1038/s41467-021-21767-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pcov_gx glycoprotein (Complex from Pangolin coronavirus)
- Glycoprotein (143 kDa, Protein from Pangolin coronavirus)
- Linoleic acid (280 Da, Ligand)