Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- A12v163-b.01 (Complex from Macaca mulatta)
- A12v163-b.01 heavy chain (Protein from Macaca mulatta)
- Quaternary complex of hiv-1 env bg505 ds-sosip with antibodies a12v163-b.01, vrc03 and pgt122. (630 kDa, Complex)
- Vrc03 light chain (Protein from Homo sapiens)
- Hiv-1 env bg505 ds-sosip gp120 (Complex from Human immunodeficiency virus 1)
- Pgt122 heavy chain (Protein from Homo sapiens)
- Hiv-1 env bg505 ds-sosip gp120 (Protein from Human immunodeficiency virus 1)
- Pgt122 light chain (Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- A12v163-b.01 light chain (Protein from Macaca mulatta)
- Vrc03 heavy chain (Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
- Hiv-1 env bg505 ds-sosip gp41 (Protein from Human immunodeficiency virus 1)
- Hiv-1 env bg505 ds-sosip gp41 (Complex from Human immunodeficiency virus 1)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6ot1
Q-score: 0.429
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 0pv-b.01 heavy (24 kDa, Protein from Macaca mulatta)
- Vrc03 light (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc03 heavy (25 kDa, Protein from Homo sapiens)
- 0pv-b.01 (Complex from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Pgt122 (Complex from Homo sapiens)
- Bg505 gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- 0pv-b.01 light (23 kDa, Protein from Macaca mulatta)
- Pgt122 heavy (25 kDa, Protein from Homo sapiens)
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-b.01, vrc03 and pgt122 (Complex)
- Pgt122 light (22 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Vrc03 (Complex from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6mph
Q-score: 0.404
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (24 kDa, Protein from Homo sapiens)
- Df1w-a.01 (Complex from Macaca mulatta)
- Df1w-a.01 fab bound to hiv-1 env bg505 ds-sosip-vrc03 fab- pgt122 fab (630 kDa, Complex)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 (Complex from Homo sapiens)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
- Df1w-a.01 heavy chain (12 kDa, Protein from Macaca mulatta)
- Df1w-a.01 light chain (12 kDa, Protein from Macaca mulatta)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6n1v
Q-score: 0.373
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Envelope glycoprotein gp4 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Pgt122 (Complex from Homo sapiens)
- Quaternary complex of hiv-1 env bg505 ds-sosip with antibodies 17d4, vrc03 and pgt122. (630 kDa, Complex)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (14 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- A12v163-a.01 heavy chain (23 kDa, Protein from Macaca mulatta)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- A12v163-a.01 (Complex from Macaca mulatta)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- A12v163-a.01 light chain (22 kDa, Protein from Macaca mulatta)
- Vrc03 (Complex from Homo sapiens)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6n1w
Q-score: 0.314
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dfph-a.15 light chain (22 kDa, Protein from Macaca mulatta)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 (Complex from Homo sapiens)
- Quaternary complex of hiv-1 env bg505 ds-sosip with antibodies dfph-a.15, vrc03 and pgt122. (630 kDa, Complex)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 (Complex from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Vrc03 heavy chain (14 kDa, Protein from Homo sapiens)
- Dfph-a.15 (Complex from Macaca mulatta)
- Dfph-a.15 heavy chain (24 kDa, Protein from Macaca mulatta)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6nf2
Q-score: 0.405
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Pgt122 light chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 heavy chain (25 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (25 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- 0pv-c.01 light chain (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 light chain (23 kDa, Protein from Homo sapiens)
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-c.01, vrc03 and pgt122 (Complex)
- 0pv-c.01 heavy chain (24 kDa, Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
- 0pv-c.01 (Complex from Homo sapiens)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6osy
Q-score: 0.396
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc03 heavy (25 kDa, Protein from Homo sapiens)
- 0pv-a.01 light (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Pgt122 (Complex from Homo sapiens)
- Bg505 gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- 0pv-a.01 (Complex from Homo sapiens)
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-a.01, vrc03 and pgt122 (Complex)
- 0pv-a.01 heavy (25 kDa, Protein from Homo sapiens)
- Pgt122 light (22 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Vrc03 light (23 kDa, Protein from Homo sapiens)
- Pgt122 heavy (25 kDa, Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6cde
Q-score: 0.443
Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD
Nat Med (2018) 24 pp. 857-867 [ Pubmed: 29867235 DOI: doi:10.1038/s41591-018-0042-6 ]
- Vrc03 heavy chain (24 kDa, Protein from Homo sapiens)
- Glycoprotein (Complex from Human immunodeficiency virus 1)
- Vfp20.01 heavy chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Pgt122 heavy chain (24 kDa, Protein from Homo sapiens)
- Vfp20.01 light chain (23 kDa, Protein from Homo sapiens)
- Glycoprotein 41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Glycoprotein 120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 light chain (22 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- Vfp20.01 (Complex from Homo sapiens)
- Vfp20.01-bg505 ds-sosip-vrc03-pgt122 (Complex)
- Vrc03 (Complex from Homo sapiens)
- Vrc03 light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6cdi
Q-score: 0.432
Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD
Nat Med (2018) 24 pp. 857-867 [ Pubmed: 29867235 DOI: doi:10.1038/s41591-018-0042-6 ]
- Vrc03 heavy chain (24 kDa, Protein from Homo sapiens)
- Glycoprotein (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Vfp16.02 heavy chain (22 kDa, Protein from Homo sapiens)
- Glycoprotein 120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Vfp16.02 light chain (23 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- Vfp16.02 (Complex from Homo sapiens)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Vfp20.01-bg505 ds-sosip-vrc03-pgt122 (Complex)
- Vrc03 (Complex from Homo sapiens)
Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD
Nat Med (2018) 24 pp. 857-867 [ Pubmed: 29867235 DOI: doi:10.1038/s41591-018-0042-6 ]
- Hiv-1 env trimer (Complex from Human immunodeficiency virus 1)
- Vfp1.01 heavy chain (Protein from Homo sapiens)
- Bg505 ds-sosip (Protein from Human immunodeficiency virus 1)
- Hiv-1 env trimer in complex with antibody (Complex from Human immunodeficiency virus 1)
- Vfp1.01 light chain (Protein from Homo sapiens)