Cryo-EM structure of human disease-associated P301L Tau amyloid fibril from mouse brain
Zhao W, Liu K, Fan Y, Zhao Q, Tao Y, Zhang M, Gan L, Yu W, Sun B, Li D, Liu C, Wang J
Cell Discov (2024) 10 pp. 27-27 [ Pubmed: 38448404 DOI: doi:10.1038/s41421-023-00637-w ]
- Island a (783 Da, Protein from Mus musculus)
- Island b (869 Da, Protein from Mus musculus)
- Tau (Tissue from Mus musculus)
- P301l tau amyloid fibril from rtg4510 mice (40 kDa, Protein from Mus musculus)
Cryo-EM structure of human alpha-fetoprotein
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8x1n
Q-score: 0.518
Liu K, Wu C, Zhu M, Xu J, Lin B, Lin H, Liu Z, Li M
Commun Biol (2024) 7 pp. 505-505 [ Pubmed: 38678117 DOI: doi:10.1038/s42003-024-06219-0 ]
- Cryo-em structure of human alpha-fetoprotein (Complex from Homo sapiens)
- Alpha-fetoprotein (68 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8wlo
Q-score: 0.429
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 prototype spike protein in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8wlr
Q-score: 0.553
Yang R, Han P, Han P, Li D, Zhao R, Niu S, Liu K, Li S, Tian WX, Gao GF
J Virol (2024) 98 pp. e0045124-e0045124 [ Pubmed: 38591877 DOI: doi:10.1128/jvi.00451-24 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 prototype spike protein receptor-binding domain in complex with hippopotamus ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (69 kDa, Protein from Hippopotamus amphibius)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8ka8
Q-score: 0.486
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ DOI: doi:10.1128/jvi.01157-23 Pubmed: 38305152 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Cryo-em structure of sars-cov-2 delta rbd in complex with golden hamster ace2 (local refinement) (Complex)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8kc2
Q-score: 0.556
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ Pubmed: 38305152 DOI: doi:10.1128/jvi.01157-23 ]
- Ba.3 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
- Cryo-em structure of sars-cov-2 ba.3 rbd in complex with golden hamster ace2 (local refinement) (Complex)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j7x
Q-score: 0.427
Bui HB, Watanabe S, Nomura N, Liu K, Uemura T, Inoue M, Tsutsumi A, Fujita H, Kinoshita K, Kato Y, Iwata S, Kikkawa M, Inaba K
Nat Commun (2023) 14 pp. 4770-4770 [ Pubmed: 37553324 DOI: doi:10.1038/s41467-023-40521-5 ]
- Light chain of yn7114-08 fab (24 kDa, Protein from Mus musculus)
- Zinc transporter 7 (43 kDa, Protein from Homo sapiens)
- Heavy chain of yn7114-08 fab (24 kDa, Protein from Mus musculus)
- Human znt7delta-his-loop-fab complex (Complex from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j7y
Q-score: 0.419
Bui HB, Watanabe S, Nomura N, Liu K, Uemura T, Inoue M, Tsutsumi A, Fujita H, Kinoshita K, Kato Y, Iwata S, Kikkawa M, Inaba K
Nat Commun (2023) 14 pp. 4770-4770 [ DOI: doi:10.1038/s41467-023-40521-5 Pubmed: 37553324 ]
- Heavy chain of yn7114-08 fab (24 kDa, Protein from Mus musculus)
- Light chain of yn7114-08 fab (24 kDa, Protein from Mus musculus)
- Human znt7delta-his-loop-fab complex (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Zinc transporter 7 (43 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8ify
Q-score: 0.382
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ Pubmed: 37676003 DOI: doi:10.1128/jvi.00505-23 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4/5 spike protein in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (125 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (76 kDa, Protein from Odocoileus virginianus)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8ifz
Q-score: 0.447
Han P, Meng Y, Zhang D, Xu Z, Li Z, Pan X, Zhao Z, Li L, Tang L, Qi J, Liu K, Gao GF
J Virol (2023) 97 pp. e0050523-e0050523 [ Pubmed: 37676003 DOI: doi:10.1128/jvi.00505-23 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (26 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron ba.4/5 spike protein receptor-binding domain in complex with white-tailed deer ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme (76 kDa, Protein from Odocoileus virginianus)