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primary_citation_author:"Lu W" AND natural_source_ncbi_code:"946362" AND resolution:[2 TO 3}
Raw consensus map of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state
Raw consensus map of TRPM2 chanzyme in the presence of Calcium and ADP-ribose.
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state
Release date: May 15, 2024
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8srd
Q-score: 0.522
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8srd
Q-score: 0.522
To Be Published
Sample:
- Trpm2 chanzyme (168 kDa, Protein from Salpingoeca rosetta)
- Cholesterol (386 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Trpm2 chanzyme incubated with magnesium and adp-ribose for 10s; adp-ribose intact; open state. (Complex from Salpingoeca rosetta)
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state
Release date: May 15, 2024
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8sre
Q-score: 0.544
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8sre
Q-score: 0.544
To Be Published
Sample:
- Water (18 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Trpm2 chanzyme (168 kDa, Protein from Salpingoeca rosetta)
- Magnesium ion (24 Da, Ligand)
- Trpm2 chanzyme incubated with magnesium and adp-ribose for 10s; adp-ribose intact; closed state. (Complex from Salpingoeca rosetta)
Release date: May 15, 2024
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8srf
Q-score: 0.54
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8srf
Q-score: 0.54
To Be Published
Sample:
- Trpm2 chanzyme (168 kDa, Protein from Salpingoeca rosetta)
- 5-o-phosphono-beta-d-ribofuranose (230 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Trpm2 chanzyme incubated with magnesium and adp-ribose for 10s; adp-ribose partially hydrolyzed; intact adp-ribose in mhr1/2 domain; adenosine monophosphate and ribose-5-phosphate in nudt9-h domain; closed state. (Complex from Salpingoeca rosetta)
- Water (18 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)