Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8srj
Q-score: 0.367
To Be Published
- Cholesterol (386 Da, Ligand)
- Trpm2 chanzyme (137 kDa, Protein from Salpingoeca rosetta)
- Trpm2 chanzyme in the presence of edta, apo state (Complex from Salpingoeca rosetta)
Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose
Resolution: 4.14 Å
EM Method: Single-particle
Fitted PDBs: 8srk
Q-score: 0.336
To Be Published
- Trpm2 chanzyme without nudt9-h bound to calcium and adpr (Complex from Salpingoeca rosetta)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Trpm2 chanzyme (137 kDa, Protein from Salpingoeca rosetta)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6plr
Q-score: 0.538
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ DOI: doi:10.1016/j.cell.2021.01.026 Pubmed: 33567265 ]
- Glycine receptor in complex with glycine (250 kDa, Complex from Danio rerio)
- Unknown ligand (128 Da, Ligand)
- N-octane (114 Da, Ligand)
- Glycine (75 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6pls
Q-score: 0.563
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- 2-aminoethanesulfonic acid (125 Da, Ligand)
- Unknown ligand (184 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Glycine receptor in complex with taurine (250 kDa, Complex from Danio rerio)
CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, closed state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6plt
Q-score: 0.516
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Unknown ligand (142 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Glycine receptor in complex with taurine (250 kDa, Complex from Danio rerio)
- 2-aminoethanesulfonic acid (125 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6plu
Q-score: 0.527
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ DOI: doi:10.1016/j.cell.2021.01.026 Pubmed: 33567265 ]
- Unknown ligand (156 Da, Ligand)
- Glycine receptor in complex with gaba (250 kDa, Complex from Danio rerio)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Gamma-amino-butanoic acid (103 Da, Ligand)
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6plv
Q-score: 0.547
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Unknown ligand (142 Da, Ligand)
- Glycine receptor in complex with gaba (250 kDa, Complex from Danio rerio)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Gamma-amino-butanoic acid (103 Da, Ligand)