multidrug transporter EfpA from Mycobacterium tuberculosis bound with lipids
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8wm5
Q-score: 0.534
Wang S, Wang K, Song K, Lai ZW, Li P, Li D, Sun Y, Mei Y, Xu C, Liao M
Nat Commun (2024) 15 pp. 7710-7710 [ Pubmed: 39231991 DOI: doi:10.1038/s41467-024-51948-9 ]
- Complex of multidrug efflux pump efpa with lipids (110 kDa, Complex from Mycobacterium tuberculosis H37Rv)
- Phosphatidylethanolamine (734 Da, Ligand)
- Efflux pump a (55 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Cardiolipin (1 kDa, Ligand)
Multidrug efflux pump MtEfpA bound with inhibitor BRD8000.3
Wang S, Wang K, Song K, Lai ZW, Li P, Li D, Sun Y, Mei Y, Xu C, Liao M
Nat Commun (2024) 15 pp. 7710-7710 [ Pubmed: 39231991 DOI: doi:10.1038/s41467-024-51948-9 ]
- Phosphatidylethanolamine (734 Da, Ligand)
- Integral membrane efflux protein efpa (55 kDa, Protein from Mycobacterium tuberculosis)
- (1s,3s)-n-[6-bromo-5-(pyrimidin-2-yl)pyridin-2-yl]-2,2-dimethyl-3-(2-methylpropyl)cyclopropane-1-carboxamide (403 Da, Ligand)
- Complex of multidrug efflux pump mtefpa with lipids and inhibitor brd8000.3 (Cellular component from Mycobacterium tuberculosis)
Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
Structure of the TbAQP2 in the apo conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8jy7
Q-score: 0.53
Chen W, Zou R, Mei Y, Li J, Xuan Y, Cui B, Zou J, Wang J, Lin S, Zhang Z, Wang C
Nat Commun (2024) 15 pp. 3985-3985 [ Pubmed: 38734677 DOI: doi:10.1038/s41467-024-48445-4 ]
- Aquaglyceroporin 2 (36 kDa, Protein from Trypanosoma brucei brucei)
- Tetramer of tbaqp2 (Complex from Trypanosoma brucei brucei)
Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidine
Resolution: 2.45 Å
EM Method: Single-particle
Fitted PDBs: 8jy8
Q-score: 0.611
Chen W, Zou R, Mei Y, Li J, Xuan Y, Cui B, Zou J, Wang J, Lin S, Zhang Z, Wang C
Nat Commun (2024) 15 pp. 3985-3985 [ Pubmed: 38734677 DOI: doi:10.1038/s41467-024-48445-4 ]
- 1,5-bis(4-amidinophenoxy)pentane (340 Da, Ligand)
- Tbaqp2 complex with pentamidine (Complex from Trypanosoma brucei brucei)
- Aquaglyceroporin 2 (33 kDa, Protein from Trypanosoma brucei brucei)
EBNA1 DNA binding domain (DBD) (458-617)+2 repeats of family repeat (FR) region
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8dlf
Q-score: 0.308
Mei Y, Messick TE, Dheekollu J, Kim HJ, Molugu S, Munoz LJC, Moiskeenkova-Bell V, Murakami K, Lieberman PM
J Virol (2022) 96 pp. e0094922-e0094922 [ DOI: doi:10.1128/jvi.00949-22 Pubmed: 36037477 ]
- 2xfr dna (56-mer) (17 kDa, DNA from Human herpesvirus 4 strain B95-8)
- Water (18 Da, Ligand)
- Epstein-barr nuclear antigen 1 (17 kDa, Protein from Human herpesvirus 4 strain B95-8)
- 2xfr dna (56-mer) (17 kDa, DNA from Human herpesvirus 4 strain B95-8)
- Ebna1 dbd+2xfr complex (Complex from Human herpesvirus 4 strain B95-8)
EBNA1 DNA binding domain (401-641) binds to half Dyad Symmetry element
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7u1t
Q-score: 0.299
To Be Published
- Dna (59-mer) (18 kDa, DNA from Human herpesvirus 4 strain B95-8)
- Ebna1 dna binding domain binds to half dyad symmetry region (160 kDa, Complex from Human herpesvirus 4 strain B95-8)
- Dna (59-mer) (18 kDa, DNA from Human herpesvirus 4 strain B95-8)
- Epstein-barr nuclear antigen 1 (19 kDa, Protein from Human herpesvirus 4 strain B95-8)
Atomic structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6q1f
Q-score: 0.213
Zhang Y, Liu W, Li Z, Kumar V, Alvarez-Cabrera AL, Leibovitch EC, Cui Y, Mei Y, Bi GQ, Jacobson S, Zhou ZH
Nat Commun (2019) 10 pp. 5346-5346 [ DOI: doi:10.1038/s41467-019-13064-x Pubmed: 31767868 ]
- Small capsomere-interacting protein (9 kDa, Protein from Human herpesvirus 6B (strain Z29))
- Human herpesvirus 6 strain z29 (Virus from Human herpesvirus 6 strain Z29)
- Triplex capsid protein 2 (33 kDa, Protein from Human herpesvirus 6B (strain Z29))
- Major capsid protein (152 kDa, Protein from Human herpesvirus 6B (strain Z29))
- Large structural phosphoprotein (95 kDa, Protein from Human herpesvirus 6B (strain Z29))
- Triplex capsid protein 1 (34 kDa, Protein from Human herpesvirus 6B (strain Z29))
Atomic Structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes
Zhang Y, Liu W, Li Z, Kumar V, Alvarez-Cabrera AL, Leibovitch EC, Cui Y, Mei Y, Bi GQ, Jacobson S, Zhou ZH
Nat Commun (2019) 10 pp. 5346-5346 [ DOI: doi:10.1038/s41467-019-13064-x Pubmed: 31767868 ]