Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules.
Seyfizadeh N, Kalbermatter D, Imhof T, Ries M, Muller C, Jenner L, Blumenschein E, Yendrzheyevskiy A, Grun F, Moog K, Eckert D, Engel R, Diebolder P, Chami M, Krauss J, Schaller T, Arndt M
J Biomed Sci (2024) 31 pp. 56-56 [ Pubmed: 38807208 DOI: doi:10.1186/s12929-024-01045-2 ]
- Hdit101 fab light chain (23 kDa, Protein from Homo sapiens)
- Trimeric hsv-1f gb ectodomain in post-fusion conformation with three bound hdit101 fab molecules (523 kDa, Complex from Homo sapiens)
- Hdit101 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Envelope glycoprotein b (100 kDa, Protein from Human alphaherpesvirus 1 strain F)
Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules.
Seyfizadeh N, Kalbermatter D, Imhof T, Ries M, Muller C, Jenner L, Blumenschein E, Yendrzheyevskiy A, Grun F, Moog K, Eckert D, Engel R, Diebolder P, Chami M, Krauss J, Schaller T, Arndt M
J Biomed Sci (2024) 31 pp. 56-56 [ Pubmed: 38807208 DOI: doi:10.1186/s12929-024-01045-2 ]
- Envelope glycoprotein b (100 kDa, Protein from Human alphaherpesvirus 1)
- Hdit102 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Hdit102 fab heavy chain (22 kDa, Protein from Homo sapiens)
- Trimeric hsv-1f gb ectodomain in post-fusion conformation with three bound hdit102 fab molecules (523 kDa, Complex from Homo sapiens)
Trimeric HSV-2F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules.
Seyfizadeh N, Kalbermatter D, Imhof T, Ries M, Muller C, Jenner L, Blumenschein E, Yendrzheyevskiy A, Grun F, Moog K, Eckert D, Engel R, Diebolder P, Chami M, Krauss J, Schaller T, Arndt M
J Biomed Sci (2024) 31 pp. 56-56 [ Pubmed: 38807208 DOI: doi:10.1186/s12929-024-01045-2 ]
- Envelope glycoprotein b (79 kDa, Protein from Human herpesvirus 2 strain G)
- Hdit101 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Hdit101 fab light chain (23 kDa, Protein from Homo sapiens)
- Trimeric hsv-2g gb ectodomain in post-fusion conformation with three bound hdit101 fab molecules (523 kDa, Complex from Homo sapiens)
Trimeric HSV-2G gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules.
Seyfizadeh N, Kalbermatter D, Imhof T, Ries M, Muller C, Jenner L, Blumenschein E, Yendrzheyevskiy A, Grun F, Moog K, Eckert D, Engel R, Diebolder P, Chami M, Krauss J, Schaller T, Arndt M
J.Biomed.Sci. (2024) 31 pp. 56-56 [ DOI: doi:10.1186/s12929-024-01045-2 Pubmed: 38807208 ]
- Hdit102 fab light chain (22 kDa, Protein from Homo sapiens)
- Hdit102 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Trimeric hsv-2g gb ectodomain in post-fusion conformation with three bound hdit101 fab molecules (523 kDa, Complex from Homo sapiens)
- Envelope glycoprotein b (79 kDa, Protein from Human herpesvirus 2 strain G)
ABC transporter NosFY, nucleotide-free in GDN
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7o0z
Q-score: 0.371
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Abc transporter nosfy (Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (33 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
ABC transporter NosDFY, nucleotide-free in lipid nanodisc
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7o13
Q-score: 0.403
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter binding protein nosd (48 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Abc transporter nosfy in complex with accessory periplasmic protein nosd (Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (33 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 7qba
Q-score: 0.45
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri)
- Nitrous-oxide reductase (71 kDa, Protein from Pseudomonas stutzeri)
- Magnesium ion (24 Da, Ligand)
- Probable abc transporter binding protein nosd (48 kDa, Protein from Pseudomonas stutzeri)
- Heteroheptamer complex of noszdfy (Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (34 kDa, Protein from Pseudomonas stutzeri)
- Calcium ion (40 Da, Ligand)
ABC transporter complex NosDFYL in GDN
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 7znq
Q-score: 0.493
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Copper-binding lipoprotein nosl (21 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Hetero-hexameric complex of nosdf2y2l (192 kDa, Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (33 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Copper (ii) ion (63 Da, Ligand)
- Probable abc transporter binding protein nosd (48 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
ABC Transporter complex NosDFYL, R-domain 1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7osf
Q-score: 0.431
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (33 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Copper-binding lipoprotein nosl (20 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Water (18 Da, Ligand)
- Copper (ii) ion (63 Da, Ligand)
- Probable abc transporter binding protein nosd (48 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Abc transporter nosfy in complex with accessory periplasmic protein nosd and cu chaperone nosl (Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
ABC Transporter complex NosDFYL, consensus refinement
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7osg
Q-score: 0.457
Muller C, Zhang L, Zipfel S, Topitsch A, Lutz M, Eckert J, Prasser B, Chami M, Lu W, Du J, Einsle O
Nature (2022) 608 pp. 626-631 [ DOI: doi:10.1038/s41586-022-05015-2 Pubmed: 35896743 ]
- Probable abc transporter permease protein nosy (29 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Probable abc transporter atp-binding protein nosf (33 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Copper-binding lipoprotein nosl (20 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Water (18 Da, Ligand)
- Copper (ii) ion (63 Da, Ligand)
- Probable abc transporter binding protein nosd (48 kDa, Protein from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Abc transporter nosfy in complex with accessory periplasmic protein nosd and cu chaperone nosl (Complex from Pseudomonas stutzeri ATCC 14405 = CCUG 16156)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)