Cryo-EM structure of the full-length human NF1 dimer
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8edm
Q-score: 0.349
Young LC, Goldstein de Salazar R, Han SW, Huang ZYS, Merk A, Drew M, Darling J, Wall V, Grisshammer R, Cheng A, Allison MR, Sale MJ, Nissley DV, Esposito D, Ognjenovic J, McCormick F
PNAS (2023) 120 pp. e2208960120-e2208960120 [ Pubmed: 36689660 DOI: doi:10.1073/pnas.2208960120 ]
- Isoform i of neurofibromin (317 kDa, Protein from Homo sapiens)
- Full-length human nf1 (320 kDa, Complex from Homo sapiens)
Cryo-EM structure of the full-length human NF1 dimer
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8edl
Q-score: 0.293
To Be Published
- Isoform i of neurofibromin (317 kDa, Protein from Homo sapiens)
- Full-length human nf1 (320 kDa, Complex from Homo sapiens)
Cryo-EM structure of the full-length human NF1 dimer
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8edn
Q-score: 0.261
To Be Published
- Full-length human nf1_body4 (320 kDa, Complex from Homo sapiens)
- Isoform i of neurofibromin (317 kDa, Protein from Homo sapiens)
Cryo-EM structure of the full-length human NF1 dimer
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8edo
Q-score: 0.477
To Be Published
- Full-length human nf1 (320 MDa, Complex from Homo sapiens)
- Neurofibromin (142 kDa, Protein from Homo sapiens)
Cryo-EM structure of the full-length human NF1 dimer
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8e20
Q-score: 0.323
Young LC, Goldstein de Salazar R, Han SW, Huang ZYS, Merk A, Drew M, Darling J, Wall V, Grisshammer R, Cheng A, Allison MR, Sale MJ, Nissley DV, Esposito D, Ognjenovic J, McCormick F
PNAS (2023) 120 pp. e2208960120-e2208960120 [ Pubmed: 36689660 DOI: doi:10.1073/pnas.2208960120 ]
- Full-length human nf1 (320 MDa, Complex from Homo sapiens)
- Isoform i of neurofibromin (317 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7syd
Q-score: 0.481
Huang Y, Ognjenovic J, Karandur D, Miller K, Merk A, Subramaniam S, Kuriyan J
eLife (2021) 10 [ Pubmed: 34846302 DOI: doi:10.7554/eLife.73218 ]
- Epidermal growth factor receptor (134 kDa, Protein from Homo sapiens)
- Epidermal growth factor (6 kDa, Protein from Homo sapiens)
- Full-length human egfr:egf complex (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sye
Q-score: 0.426
Huang Y, Ognjenovic J, Karandur D, Miller K, Merk A, Subramaniam S, Kuriyan J
eLife (2021) 10 [ Pubmed: 34846302 DOI: doi:10.7554/eLife.73218 ]
- Full-length human egfr:egf complex (Complex)
- Epidermal growth factor receptor (134 kDa, Protein from Homo sapiens)
- Epidermal growth factor (6 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sz0
Q-score: 0.463
Huang Y, Ognjenovic J, Karandur D, Miller K, Merk A, Subramaniam S, Kuriyan J
eLife (2021) 10 [ Pubmed: 34846302 DOI: doi:10.7554/eLife.73218 ]
- Epidermal growth factor receptor (134 kDa, Protein from Homo sapiens)
- Full-length human egfr(l834r):egf complex (Complex)
- Epidermal growth factor (6 kDa, Protein from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7sz1
Q-score: 0.413
Huang Y, Ognjenovic J, Karandur D, Miller K, Merk A, Subramaniam S, Kuriyan J
eLife (2021) 10 [ Pubmed: 34846302 DOI: doi:10.7554/eLife.73218 ]
- Full-length human egfr(l834r):egf complex (Complex)
- Epidermal growth factor (6 kDa, Protein from Homo sapiens)
- Epidermal growth factor receptor (134 kDa, Protein from Homo sapiens)