Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9b8y
Q-score: 0.458
Hu J, Park SJ, Walter T, Orozco IJ, O'Dea G, Ye X, Du J, Lu W
Nature (2024) 630 pp. 509-515 [ Pubmed: 38750366 DOI: doi:10.1038/s41586-024-07436-7 ]
- Decavanadate (957 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (134 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Cryo-em structure of the human trpm4 channel in complex with calcium and decavanadate at 37 degrees celsius (Complex from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9b8z
Q-score: 0.451
Hu J, Park SJ, Walter T, Orozco IJ, O'Dea G, Ye X, Du J, Lu W
Nature (2024) 630 pp. 509-515 [ Pubmed: 38750366 DOI: doi:10.1038/s41586-024-07436-7 ]
- Decavanadate (957 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (134 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Human trpm4 channel subunit in complex with calcium and decavanadate at 37 degrees celsius (Complex from Homo sapiens)
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9b90
Q-score: 0.411
Hu J, Park SJ, Walter T, Orozco IJ, O'Dea G, Ye X, Du J, Lu W
Nature (2024) 630 pp. 509-515 [ Pubmed: 38750366 DOI: doi:10.1038/s41586-024-07436-7 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 4 (134 kDa, Protein from Homo sapiens)
- Cryo-em structure of the human trpm4 channel in complex with calcium and atp at 37 degrees celsius (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9b91
Q-score: 0.425
Hu J, Park SJ, Walter T, Orozco IJ, O'Dea G, Ye X, Du J, Lu W
Nature (2024) 630 pp. 509-515 [ Pubmed: 38750366 DOI: doi:10.1038/s41586-024-07436-7 ]
- Transient receptor potential cation channel subfamily m member 4 (134 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Cryo-em structure of the human trpm4 channel subunit in complex with calcium and atp at 37 degrees celsius (Complex from Homo sapiens)
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius