Cryo-EM structure of DDB1deltaB-DDA1-DCAF5
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 8tl6
Q-score: 0.598
Radko-Juettner S, Yue H, Myers JA, Carter RD, Robertson AN, Mittal P, Zhu Z, Hansen BS, Donovan KA, Hunkeler M, Rosikiewicz W, Wu Z, McReynolds MG, Roy Burman SS, Schmoker AM, Mageed N, Brown SA, Mobley RJ, Partridge JF, Stewart EA, Pruett-Miller SM, Nabet B, Peng J, Gray NS, Fischer ES, Roberts CWM
Nature (2024) 628 pp. 442-449 [ DOI: doi:10.1038/s41586-024-07250-1 Pubmed: 38538798 ]
- Complex of ddb1deltab-dda1-dcaf5 (220 kDa, Complex from Homo sapiens)
- Dna damage-binding protein 1 (96 kDa, Protein from Homo sapiens)
- Det1- and ddb1-associated protein 1 (14 kDa, Protein from Homo sapiens)
- Ddb1- and cul4-associated factor 5 (108 kDa, Protein from Homo sapiens)
Chung K, Xu L, Chai P, Peng J, Devarkar SC, Pyle AM
Science (2022) 378 pp. 627-634 [ Pubmed: 36356138 DOI: 10.1126/science.abq2844 ]
Image sets:
CryoEM micrographs of a group II intron retroelement (apoRNP)
Chung K, Xu L, Chai P, Peng J, Devarkar SC, Pyle AM
Science (2022) 378 pp. 627-634 [ Pubmed: 36356138 DOI: 10.1126/science.abq2844 ]
Image sets:
CryoEM Structure of an Group II Intron Retroelement (apo-complex)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uim
Q-score: 0.262
Chung K, Xu L, Chai P, Peng J, Devarkar SC, Pyle AM
Science (2022) 378 pp. 627-634 [ Pubmed: 36356138 DOI: doi:10.1126/science.abq2844 ]
- Ammonium ion (18 Da, Ligand)
- E.r iic intron (206 kDa, RNA from [Eubacterium] rectale)
- Complex of rna and protein (250 kDa, Complex from [Eubacterium] rectale)
- Magnesium ion (24 Da, Ligand)
- Group ii intron reverse transcriptase/maturase (49 kDa, Protein from [Eubacterium] rectale)
CryoEM Structure of an Group II Intron Retroelement
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uin
Q-score: 0.467
Chung K, Xu L, Chai P, Peng J, Devarkar SC, Pyle AM
Science (2022) 378 pp. 627-634 [ Pubmed: 36356138 DOI: doi:10.1126/science.abq2844 ]
- Magnesium ion (24 Da, Ligand)
- Ternary complex of rna, protein and dna (260 kDa, Complex from [Eubacterium] rectale)
- Water (18 Da, Ligand)
- Ammonium ion (18 Da, Ligand)
- Group ii intron reverse transcriptase/maturase (49 kDa, Protein from [Eubacterium] rectale)
- Dna (37-mer) (11 kDa, DNA from [Eubacterium] rectale)
- E.r iic intron (206 kDa, RNA from [Eubacterium] rectale)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7lht
Q-score: 0.376
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Lrrk2 (Complex from Homo sapiens)
Structure of the LRRK2 monomer
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7lhw
Q-score: 0.406
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Lrrk2 (Complex from Homo sapiens)
Structure of the LRRK2 G2019S mutant
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7li3
Q-score: 0.402
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Lrrk2 g2019s mutant (Complex from Homo sapiens)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
Structure of LRRK2 after symmetry expansion
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7li4
Q-score: 0.491
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Lrrk2 (Complex from Homo sapiens)