Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 1
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ DOI: doi:10.1016/j.celrep.2024.114307 Pubmed: 38848216 ]
Structure of SARS-CoV-2 (HP-GSAS-Mut7) spike in complex with TXG-0078 Fab -Conformation 2
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ DOI: doi:10.1016/j.celrep.2024.114307 Pubmed: 38848216 ]
Local refinement of SARS-CoV-2 (HP-GSAS-Mut7) spike NTD in complex with TXG-0078 Fab
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B
Cell Rep (2024) 43 pp. 114307-114307 [ DOI: doi:10.1016/j.celrep.2024.114307 Pubmed: 38848216 ]
- Txg-0078 fab heavy chain (16 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of sars-cov-2(hp-gsas-mut7) spike in complex with txg-0078 fab- local refinement (Complex from Severe acute respiratory syndrome coronavirus 2)
- Txg-0078 fab light chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8oyu
Q-score: 0.145
Cornish K, Huo J, Jones L, Sharma P, Thrush JW, Abdelkarim S, Kipar A, Ramadurai S, Weckener M, Mikolajek H, Liu S, Buckle I, Bentley E, Kirby A, Han X, Laidlaw SM, Hill M, Eyssen L, Norman C, Le Bas A, Clarke J, James W, Stewart JP, Carroll M, Naismith JH, Owens RJ
Open Biol (2024) 14 pp. 230252-230252 [ DOI: doi:10.1098/rsob.230252 Pubmed: 38835241 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of stabilised hexapro omicron ba.1 spike trimer with two h6 nanobodies (Complex)
- Spike glycoprotein,fibritin (139 kDa, Protein from Enterobacteria phage T4)
- H6 nanobody (13 kDa, Protein from Lama glama)
- H6 nanobody (Complex from Lama glama)
- Stabilised hexapro omicron ba.1 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
Atomic structure of wheat ribosome reveals unique features of the plant ribosomes
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8jiv
Q-score: 0.649
Mishra RK, Sharma P, Khaja FT, Uday AB, Hussain T
Structure (2024) 32 pp. 562- [ Pubmed: 38458197 DOI: doi:10.1016/j.str.2024.02.006 ]
- The large subunit of wheat ribosome (Complex from Triticum aestivum)
- Ribosomal protein l37 (10 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l7a (29 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l4 c-terminal domain-containing protein (44 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein el33 (12 kDa, Protein from Triticum aestivum)
- Ubiquitin-like domain-containing protein (14 kDa, Protein from Triticum aestivum)
- Ribosomal l28e/mak16 domain-containing protein (16 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein ul22 (19 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l11 (20 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l34 (13 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l35 (14 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l31 (14 kDa, Protein from Triticum aestivum)
- 5.8s rrna (50 kDa, RNA from Triticum aestivum)
- 60s ribosomal protein l13 (24 kDa, Protein from Triticum aestivum)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l36 (12 kDa, Protein from Triticum aestivum)
- Zinc ion (65 Da, Ligand)
- 5s rrna (38 kDa, RNA from Triticum aestivum)
- Ribosomal protein l18e/l15p domain-containing protein (16 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l38 (8 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l21 (18 kDa, Protein from Triticum aestivum)
- Ribosomal protein l10e/l16 domain-containing protein (24 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l27 (15 kDa, Protein from Triticum aestivum)
- Genome assembly, chromosome: ii (12 kDa, Protein from Triticum aestivum)
- Ribosomal protein l19 (24 kDa, Protein from Triticum aestivum)
- Magnesium ion (24 Da, Ligand)
- Ribosomal protein l39 (6 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein el32 (15 kDa, Protein from Triticum aestivum)
- Genome assembly, chromosome: ii (16 kDa, Protein from Triticum aestivum)
- Ribosomal protein l6 alpha-beta domain-containing protein (21 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l18a (21 kDa, Protein from Triticum aestivum)
- Trash domain-containing protein (18 kDa, Protein from Triticum aestivum)
- Ribosomal protein l7ae/l30e/s12e/gadd45 domain-containing protein (12 kDa, Protein from Triticum aestivum)
- Ribosomal protein l13a (23 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein ul30 (28 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l37a, expressed (10 kDa, Protein from Triticum aestivum)
- Genome assembly, chromosome: ii (14 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l29 (6 kDa, Protein from Triticum aestivum)
- Ribosomal protein l18e/l15p domain-containing protein (21 kDa, Protein from Triticum aestivum)
- Ribosomal protein l17 (14 kDa, Protein from Triticum aestivum)
- Ribosomal protein l15 (24 kDa, Protein from Triticum aestivum)
- Kow domain-containing protein (14 kDa, Protein from Triticum aestivum)
- Ribosomal protein l3 (44 kDa, Protein from Triticum aestivum)
- Ribosomal protein l5 eukaryotic c-terminal domain-containing protein (35 kDa, Protein from Triticum aestivum)
- 60s ribosomal protein l6 (25 kDa, Protein from Triticum aestivum)
- Ribosomal protein l2 c-terminal domain-containing protein (28 kDa, Protein from Triticum aestivum)
- Ribosomal protein l14e domain-containing protein (15 kDa, Protein from Triticum aestivum)
- 25s rrna (1 MDa, RNA from Triticum aestivum)
Atomic structure of wheat ribosome reveals unique features of the plant ribosomes
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8jiw
Q-score: 0.481
Mishra RK, Sharma P, Khaja FT, Uday AB, Hussain T
Structure (2024) 32 pp. 562- [ Pubmed: 38458197 DOI: doi:10.1016/j.str.2024.02.006 ]
- Ribosomal protein s10 domain-containing protein (13 kDa, Protein from Triticum aestivum)
- Mitogen-activated protein kinase (36 kDa, Protein from Triticum aestivum)
- Potassium ion (39 Da, Ligand)
- 40s ribosomal protein s11 n-terminal domain-containing protein (18 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s6 (28 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s4 (30 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s8 (25 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s18 (17 kDa, Protein from Triticum aestivum)
- 30s ribosomal protein s8, chloroplastic (14 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s15 (17 kDa, Protein from Triticum aestivum)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s7 (22 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s26 (15 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s14 (16 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s24 (15 kDa, Protein from Triticum aestivum)
- 18s rrna (584 kDa, RNA from Triticum aestivum)
- S5 drbm domain-containing protein (30 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s29 (6 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s17 (16 kDa, Protein from Triticum aestivum)
- Ribosomal protein s13/s15 n-terminal domain-containing protein (17 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s30 (6 kDa, Protein from Triticum aestivum)
- The large subunit of wheat ribosome (Complex from Triticum aestivum)
- 60s ribosomal protein l41 (3 kDa, Protein from Triticum aestivum)
- Plectin/s10 n-terminal domain-containing protein (20 kDa, Protein from Triticum aestivum)
- 30s ribosomal protein s4, chloroplastic (22 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s27 (9 kDa, Protein from Triticum aestivum)
- Zinc ion (65 Da, Ligand)
- Ribosomal protein s7 domain-containing protein (22 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s3a (30 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s23 (15 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s28 (7 kDa, Protein from Triticum aestivum)
- Kh type-2 domain-containing protein (25 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s19 (17 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s21 (9 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s25 (10 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein sa (32 kDa, Protein from Triticum aestivum)
- 40s ribosomal protein s16 (16 kDa, Protein from Triticum aestivum)
Atomic structure of wheat ribosome reveals unique features of the plant ribosomes
Atomic structure of wheat ribosome reveals unique features of the plant ribosomes
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7uow
Q-score: 0.268
Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, Cheedarla N, Verkerke HP, Frank F, Neish AS, Roback JD, Davis CW, Wrammert J, Ahmed R, Suthar MS, Sharma A, Murali-Krishna K, Chandele A, Ortlund EA
Structure (2023) 31 pp. 801-811.e5 [ Pubmed: 37167972 DOI: doi:10.1016/j.str.2023.04.010 ]
- Monoclonal antibody 034_32 heavy chain (48 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Monoclonal antibody 034_32 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Sars-cov2 spike trimer in complex with monoclonal antibody (Complex)
- Mab 034-32 heavy chain, mab 034-32 light chain (Complex from Homo sapiens)
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-02
Resolution: 3.86 Å
EM Method: Single-particle
Fitted PDBs: 7u0q
Q-score: 0.324
Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, Cheedarla N, Verkerke HP, Frank F, Neish AS, Roback JD, Davis CW, Wrammert J, Ahmed R, Suthar MS, Sharma A, Murali-Krishna K, Chandele A, Ortlund EA
Structure (2023) 31 pp. 801-811.e5 [ Pubmed: 37167972 DOI: doi:10.1016/j.str.2023.04.010 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cov2 spike timer in complex with monoclonal antibody (Complex)
- Mab 002-02 heavy chain (49 kDa, Protein from Homo sapiens)
- Mab 002-02 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Mab 002-02 light chain, mab 002-02 heavy chain (Complex from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)