Cryo-EM structure of the Tocilizumab Fab/IL-6R complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8j6f
Q-score: 0.459
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The tocilizumab fab/il-6r complex (Complex from Homo sapiens)
- Il6r-d2 peptide (1 kDa, Protein from Homo sapiens)
- Heavy chain of tocilizumab fab (24 kDa, Protein from Homo sapiens)
- Interleukin-6 receptor subunit alpha (40 kDa, Protein from Homo sapiens)
- Light chain of tocilizumab fab (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of the sarilumab Fab/IL-6R complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iow
Q-score: 0.497
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Interleukin-6 receptor subunit alpha (40 kDa, Protein from Homo sapiens)
- Heavy chain of sarilumab fab (23 kDa, Protein from Homo sapiens)
- The sarilumab fab/il-6r complex (Complex from Homo sapiens)
- Light chain of sarilumab fab (23 kDa, Protein from Homo sapiens)
Structure of the human CLC-7/Ostm1 complex reveals a novel state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8hvt
Q-score: 0.498
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Osteopetrosis-associated transmembrane protein 1 (37 kDa, Protein from Homo sapiens)
- H(+)/cl(-) exchange transporter 7 (88 kDa, Protein from Homo sapiens)
- Clc-7/ostm1 (Complex from Homo sapiens)
Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ytw
Q-score: 0.507
Wang M, He J, Li S, Cai Q, Zhang K, She J
Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]
- Ascorbic acid (176 Da, Ligand)
- Water (18 Da, Ligand)
- Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)
- Svct1 (Complex from Mus musculus)
- Sodium ion (22 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yty
Q-score: 0.447
Wang M, He J, Li S, Cai Q, Zhang K, She J
Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]
- Svct1 (Complex from Mus musculus)
- Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)
Structure of Arabidopsis thaliana CLCa
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 7xa9
Q-score: 0.583
He J, Wang M, Li S, Chen L, Zhang K, She J
J Biol Chem (2023) 299 pp. 102833-102833 [ DOI: doi:10.1016/j.jbc.2022.102833 Pubmed: 36581207 ]
- Nitrate ion (62 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Chloride channel protein clc-a (88 kDa, Protein from Arabidopsis thaliana)
- Atclca (Complex from Arabidopsis thaliana)
Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y
eLife (2020) 9 [ Pubmed: 32762847 DOI: doi:10.7554/eLife.60513 ]
- Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)