Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y
eLife (2020) 9 [ Pubmed: 32762847 DOI: doi:10.7554/eLife.60513 ]
- Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y
eLife (2020) 9 [ Pubmed: 32762847 DOI: doi:10.7554/eLife.60513 ]
- Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
MCU holocomplex in High-calcium state
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 6xjv
Q-score: 0.31
Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y
eLife (2020) 9 [ Pubmed: 32762847 DOI: doi:10.7554/eLife.60513 ]
- Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
- Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
- Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
- Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
- Calcium uptake protein 2, mitochondrial (49 kDa, Protein from Homo sapiens)
MCU holocomplex in Low-calcium blocking state
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6xjx
Q-score: 0.308
Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y
eLife (2020) 9 [ Pubmed: 32762847 DOI: doi:10.7554/eLife.60513 ]
- Calcium uptake protein 2, mitochondrial (49 kDa, Protein from Homo sapiens)
- Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
- Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
- Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
- Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Human MCU-EMRE complex, dimer of channel
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6o58
Q-score: 0.381
Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y
Cell (2019) 177 pp. 1252- [ DOI: doi:10.1016/j.cell.2019.03.050 Pubmed: 31080062 ]
- Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
- Mcu/emre complex (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Human MCU-EMRE complex, monomer of channel
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6o5b
Q-score: 0.447
Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y
Cell (2019) 177 pp. 1252- [ Pubmed: 31080062 DOI: doi:10.1016/j.cell.2019.03.050 ]
- Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
- Mcu/emre complex (Complex from Homo sapiens)
Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y
Cell (2019) 177 pp. 1252-1261.e13 [ DOI: doi:10.1016/j.cell.2019.03.050 Pubmed: 31080062 ]
- Mcu (Protein from Homo sapiens)
- Mcu (Complex from Homo sapiens)
Cryo-EM structure of OTOP3 from xenopus tropicalis
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 6o84
Q-score: 0.427
Cryo-EM structure of human TPC2 channel in the ligand-bound open state
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6nq0
Q-score: 0.455
Cryo-EM structure of human TPC2 channel in the apo state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6nq1
Q-score: 0.441
She J, Zeng W, Guo J, Chen Q, Bai X, Jiang Y
eLife (2019) 8 [ DOI: doi:10.7554/eLife.45222 Pubmed: 30860481 ]
- Two pore calcium channel protein 2 (85 kDa, Protein from Homo sapiens)
- Two-pore channel 2 (Complex from Homo sapiens)