Cryo-EM structure of the SS-14-bound human SSTR2-Gi1 complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7wic
Q-score: 0.509
Chen LN, Wang WW, Dong YJ, Shen DD, Guo J, Yu X, Qin J, Ji SY, Zhang H, Shen Q, He Q, Yang B, Zhang Y, Li Q, Mao C
Cell Res (2022) 32 pp. 785-788 [ Pubmed: 35578016 DOI: doi:10.1038/s41422-022-00669-z ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Somatostatin-14 (1 kDa, Protein from Homo sapiens)
- Somatostatin receptor type 2 (Complex from Homo sapiens)
- Antibody (Complex from synthetic construct)
- Somatostatin receptor type 2 (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Single fab chain (svfv16) (28 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cryo-em structure of the ss-14-bound sstr2-gi1 complex (180 kDa, Complex)
- G protein (Complex from Homo sapiens)
Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7wig
Q-score: 0.527
Chen LN, Wang WW, Dong YJ, Shen DD, Guo J, Yu X, Qin J, Ji SY, Zhang H, Shen Q, He Q, Yang B, Zhang Y, Li Q, Mao C
Cell Res (2022) 32 pp. 785-788 [ Pubmed: 35578016 DOI: doi:10.1038/s41422-022-00669-z ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- ~{n}-[(2~{r})-1-[[(1~{r},3~{s})-3-(aminomethyl)cyclohexyl]methylamino]-3-(1~{h}-indol-3-yl)-1-oxidanylidene-propan-2-yl]spiro[indene-1,4'-piperidine]-1'-carboxamide (539 Da, Ligand)
- Somatostatin receptor type 2 (Complex from Homo sapiens)
- Cryo-em structure of the l-054,264-bound sstr2-gi1 complex (180 kDa, Complex)
- Somatostatin receptor type 2 (41 kDa, Protein from Homo sapiens)
- Antibody (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Single fab chain (svfv16) (28 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- G protein (Complex from Homo sapiens)
Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state.
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7c7s
Q-score: 0.508
Mao C, Shen C, Li C, Shen DD, Xu C, Zhang S, Zhou R, Shen Q, Chen LN, Jiang Z, Liu J, Zhang Y
Cell Res (2020) 30 pp. 564-573 [ DOI: doi:10.1038/s41422-020-0350-5 Pubmed: 32494023 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gamma-aminobutyric acid type b receptor subunit 2 (91 kDa, Protein from Homo sapiens)
- The cgp54626-bound gabab heterodimer (Complex from Homo sapiens)
- (r)-(cyclohexylmethyl)[(2s)-3-{[(1s)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid (408 Da, Ligand)
- Gamma-aminobutyric acid type b receptor subunit 1 (105 kDa, Protein from Homo sapiens)