Histamine-bound H4R/Gi complex
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8jxt
Q-score: 0.472
Xia R, Shi S, Xu Z, Vischer HF, Windhorst AD, Qian Y, Duan Y, Liang J, Chen K, Zhang A, Guo C, Leurs R, He Y
Nat Commun (2024) 15 pp. 2493-2493 [ DOI: doi:10.1038/s41467-024-46840-5 Pubmed: 38509098 ]
- Gpcr/g-protein complex (130 MDa, Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Histamine (111 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Histamine h4 receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Saccharomyces cerevisiae spliceosomal E complex (UBC4)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6n7p
Q-score: 0.352
Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao R
Nature (2019) 573 pp. 375-380 [ DOI: doi:10.1038/s41586-019-1523-6 Pubmed: 31485080 ]
- Protein nam8 (57 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing factor 39 (74 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Protein luc7 (30 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein 70 kda homolog (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Nuclear cap-binding protein complex subunit 1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubc4 pre-mrna (81 kDa, RNA from Saccharomyces cerevisiae S288C)
- 56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein a (40 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Saccharomyces cerevisiae spliceosomal e complex (ebc4) (Complex from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing protein prp40 (69 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 snrna (182 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Nuclear cap-binding protein subunit 2 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein component snu71,u1 small nuclear ribonucleoprotein component snu71,snu71 (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Saccharomyces cerevisiae spliceosomal E complex (ACT1)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6n7r
Q-score: 0.427
Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao R
Nature (2019) 573 pp. 375-380 [ DOI: doi:10.1038/s41586-019-1523-6 Pubmed: 31485080 ]
- Protein nam8 (57 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Pre-mrna-processing factor 39 (74 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Protein luc7 (30 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Saccharomyces cerevisiae spliceosomal e complex (act1) (Complex from Saccharomyces cerevisiae)
- U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein 70 kda homolog (34 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein a (40 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Act1 pre-mrna (70 kDa, RNA from Saccharomyces cerevisiae S288C)
- U1 snrna (182 kDa, RNA from Saccharomyces cerevisiae)
- Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- U1 small nuclear ribonucleoprotein component snu71,u1 small nuclear ribonucleoprotein component snu71,snu71 (9 kDa, Protein from Saccharomyces cerevisiae S288C)
cryo-EM structure of archaeal Ribonuclease P with mature tRNA
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6k0b
Q-score: 0.221
Wan F, Wang Q, Tan J, Tan M, Chen J, Shi S, Lan P, Wu J, Lei M
Nat Commun (2019) 10 pp. 2617-2617 [ Pubmed: 31197137 DOI: doi:10.1038/s41467-019-10496-3 ]
- Ribonuclease p protein component 1 (10 kDa, Protein from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440))
- Ribonuclease p protein component 4 (15 kDa, Protein from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440))
- Ribonuclease p protein component 2 (15 kDa, Protein from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440))
- Cryo-em structure of archaeal ribonuclease p with mature trna (Complex from Methanocaldococcus jannaschii)
- Ribonuclease p protein component 3 (27 kDa, Protein from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440))
- Rpr (83 kDa, RNA from Methanocaldococcus jannaschii)
- Zinc ion (65 Da, Ligand)
- Trna (26 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l7ae (12 kDa, Protein from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440))
Cryo-EM structure of human Ribonuclease P
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 6ahr
Q-score: 0.224
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q, Chen J, Shi S, Lan P, Lei M
Cell (2018) 175 pp. 1393-1404.e11 [ DOI: doi:10.1016/j.cell.2018.10.003 Pubmed: 30454648 ]
- Ribonuclease p protein subunit p20 (15 kDa, Protein from Homo sapiens)
- Ribonucleases p/mrp protein subunit pop1 (114 kDa, Protein from Homo sapiens)
- Rnase p (Complex from Homo sapiens)
- H1 rna (110 kDa, RNA from Homo sapiens)
- Ribonuclease p protein subunit p21 (17 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p29 (25 kDa, Protein from Homo sapiens)
- Ribonuclease p/mrp protein subunit pop5 (18 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p38 (31 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p30 (29 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p14 (13 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p40 (41 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ribonuclease p protein subunit p25 (20 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Ribonuclease P with mature tRNA
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 6ahu
Q-score: 0.288
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q, Chen J, Shi S, Lan P, Lei M
Cell (2018) 175 pp. 1393-1404.e11 [ DOI: doi:10.1016/j.cell.2018.10.003 Pubmed: 30454648 ]
- Ribonuclease p protein subunit p20 (15 kDa, Protein from Homo sapiens)
- Ribonucleases p/mrp protein subunit pop1 (114 kDa, Protein from Homo sapiens)
- Trna (23 kDa, RNA from Homo sapiens)
- Rnase p (Complex from Homo sapiens)
- Rna (Complex from Homo sapiens)
- H1 rna (110 kDa, RNA from Homo sapiens)
- Ribonuclease p protein subunit p21 (17 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p29 (25 kDa, Protein from Homo sapiens)
- Ribonuclease p/mrp protein subunit pop5 (18 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p38 (31 kDa, Protein from Homo sapiens)
- Rnase p with trna (Complex)
- Ribonuclease p protein subunit p30 (29 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p14 (13 kDa, Protein from Homo sapiens)
- Ribonuclease p protein subunit p40 (41 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Ribonuclease p protein subunit p25 (20 kDa, Protein from Homo sapiens)
Cryo-EM structure of yeast Ribonuclease P
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 6agb
Q-score: 0.311
Lan P, Tan M, Zhang Y, Niu S, Chen J, Shi S, Qiu S, Wang X, Peng X, Cai G, Cheng H, Wu J, Li G, Lei M
Science (2018) 362 [ DOI: doi:10.1126/science.aat6678 Pubmed: 30262633 ]
- Ribonuclease p protein subunit rpr2 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Rnase p (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Ribonuclease p/mrp protein subunit pop5 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop8 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Rnases mrp/p 32.9 kda subunit (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p rna (118 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop7 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop6 (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p/mrp protein subunit rpp1 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 6ah3
Q-score: 0.259
Lan P, Tan M, Zhang Y, Niu S, Chen J, Shi S, Qiu S, Wang X, Peng X, Cai G, Cheng H, Wu J, Li G, Lei M
Science (2018) 362 [ DOI: doi:10.1126/science.aat6678 Pubmed: 30262633 ]
- Ribonuclease p protein subunit rpr2 (16 kDa, Protein from Baker's yeast)
- Rnase p (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop3 (22 kDa, Protein from Baker's yeast)
- Pre-trna (25 kDa, RNA from Saccharomyces cerevisiae S288c)
- Rnases mrp/p 32.9 kda subunit (32 kDa, Protein from Baker's yeast)
- Ribonucleases p/mrp protein subunit pop1 (100 kDa, Protein from Baker's yeast)
- Ribonucleases p/mrp protein subunit pop6 (18 kDa, Protein from Baker's yeast)
- Ribonuclease p rna (118 kDa, RNA from Baker's yeast)
- Rnase p with pre-trna substrate (Complex)
- Ribonuclease p/mrp protein subunit rpp1 (32 kDa, Protein from Baker's yeast)
- Ribonuclease p/mrp protein subunit pop5 (19 kDa, Protein from Baker's yeast)
- Ribonucleases p/mrp protein subunit pop7 (15 kDa, Protein from Baker's yeast)
- Pre-trna (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop8 (15 kDa, Protein from Baker's yeast)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)