Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wm4
Q-score: 0.256
Sakaniwa K, Fujimura A, Shibata T, Shigematsu H, Ekimoto T, Yamamoto M, Ikeguchi M, Miyake K, Ohto U, Shimizu T
Nat Commun (2023) 14 pp. 164-164 [ DOI: doi:10.1038/s41467-023-35844-2 Pubmed: 36631495 ]
- Rna (81-mer) (25 kDa, RNA from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toll-like receptor 3 (77 kDa, Protein from Mus musculus)
- Rna (81-mer) (25 kDa, RNA from synthetic construct)
- Tetrameric tlr3 in complex with dsrna (90 bp) (Complex from Mus musculus)
Cryo-EM reconstruction of TLR7/Cpd-3 (SM-394830) complex in closed form
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T
Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]
- Tlr7/cpd-3 (sm-394830) complex (200 kDa, Complex from Macaca mulatta)
Cryo-EM reconstruction of TLR7/Cpd-6 (DSR-139293) complex in closed form
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T
Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]
- Tlr7/cpd-6 (dsr-139293) complex (200 kDa, Complex from Macaca mulatta)
Cryo-EM reconstruction of TLR7/Cpd-6 (DSR-139293) complex in open form
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T
Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]
- Tlr7/cpd-6 (dsr-139293) complex (200 kDa, Complex from Macaca mulatta)
Cryo-EM reconstruction of TLR7/Cpd-7 (DSR-139970) complex in open form
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T
Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]
- Tlr7/cpd-7 (dsr-139970) complex (200 kDa, Complex from Macaca mulatta)
Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6lw1
Q-score: 0.54
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T
Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]