Electron Microscopy Data Bank

EMD-5601

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Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 26.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ Pubmed: 23624860 DOI: doi:10.1038/nsmb.2564 ]

Sample:

Human dicer (220 kDa, Sample)
Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)

EMD-5602

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Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 29.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]

Sample:

Human dicer in complex with a 35 bp pre-sirna (250 kDa, Sample)
Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
35 bp pre-sirna (24 kDa, RNA from Homo sapiens)

EMD-5603

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Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 31.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ Pubmed: 23624860 DOI: doi:10.1038/nsmb.2564 ]

Sample:

Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Human dicer in complex with pre-let7 (250 kDa, Sample)
Pre-let7 (24 kDa, Macromolecule from Homo sapiens)

EMD-5604

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Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 26.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]

Sample:

Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Human dicer-pact heterodimer in closed conformation (260 kDa, Sample)

EMD-5605

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Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 26.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ Pubmed: 23624860 DOI: doi:10.1038/nsmb.2564 ]

Sample:

Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Human dicer-pact heterodimer in canonical conformation (260 kDa, Sample)

EMD-5606

Download Map 3D View

Substrate-specific structural rearrangements of human Dicer

Release date: May 1, 2013
Resolution: 26.0 Å
EM Method: Single-particle

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW

Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]

Sample:

Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Human dicer-pact heterodimer in open conformation (260 kDa, Sample)

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