Cryo-EM structure of human TLR3 in complex with UNC93B1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7c76
Q-score: 0.437
Ishida H, Asami J, Zhang Z, Nishizawa T, Shigematsu H, Ohto U, Shimizu T
Nat Struct Mol Biol (2021) 28 pp. 173-180 [ Pubmed: 33432245 DOI: doi:10.1038/s41594-020-00542-w ]
- Toll-like receptor 3 (103 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Protein unc-93 homolog b1 (66 kDa, Protein from Homo sapiens)
- Complex of tlr3 and unc93b1 (Complex from Homo sapiens)
Cryo-EM structure of mouse TLR3 in complex with UNC93B1
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7c77
Q-score: 0.424
Ishida H, Asami J, Zhang Z, Nishizawa T, Shigematsu H, Ohto U, Shimizu T
Nat Struct Mol Biol (2021) 28 pp. 173-180 [ Pubmed: 33432245 DOI: doi:10.1038/s41594-020-00542-w ]
- Toll-like receptor 3 (103 kDa, Protein from Mus musculus)
- Protein unc-93 homolog b1 (67 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of tlr3 and unc93b1 (Complex from Mus musculoides)
Cryo-EM structure of human TLR7 in complex with UNC93B1
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7cyn
Q-score: 0.243
Ishida H, Asami J, Zhang Z, Nishizawa T, Shigematsu H, Ohto U, Shimizu T
Nat Struct Mol Biol (2021) 28 pp. 173-180 [ Pubmed: 33432245 DOI: doi:10.1038/s41594-020-00542-w ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of tlr7 and unc93b1 (Complex from Homo sapiens)
- Toll-like receptor 7 (121 kDa, Protein from Homo sapiens)
- Protein unc-93 homolog b1 (66 kDa, Protein from Homo sapiens)
Structure of a Group II Intron Complexed with its Reverse Transcriptase
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5g2x
Q-score: 0.158
Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW
Nat Struct Mol Biol (2016) 23 pp. 549-557 [ Pubmed: 27136327 DOI: doi:10.1038/NSMB.3220 ]
Structure of a Group II Intron Complexed with its Reverse Transcriptase
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 5g2y
Q-score: 0.155
Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW
Nat Struct Mol Biol (2016) 23 pp. 549-557 [ Pubmed: 27136327 DOI: doi:10.1038/NSMB.3220 ]
- Group ii intron (RNA from Lactococcus lactis)
- Structure a of group ii intron (290 kDa, Sample)
- Reverse transcriptase (Protein from Lactococcus lactis)
Structure of a Group II Intron Complexed with its Reverse Transcriptase
Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW
Nat Struct Mol Biol (2016) 23 pp. 549-557 [ Pubmed: 27136327 DOI: doi:10.1038/NSMB.3220 ]
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ Pubmed: 23624860 DOI: doi:10.1038/nsmb.2564 ]
- Human dicer (220 kDa, Sample)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Human dicer in complex with a 35 bp pre-sirna (250 kDa, Sample)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
- 35 bp pre-sirna (24 kDa, RNA from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ Pubmed: 23624860 DOI: doi:10.1038/nsmb.2564 ]
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
- Human dicer in complex with pre-let7 (250 kDa, Sample)
- Pre-let7 (24 kDa, Macromolecule from Homo sapiens)
Substrate-specific structural rearrangements of human Dicer
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol (2013) 20 pp. 662-670 [ DOI: doi:10.1038/nsmb.2564 Pubmed: 23624860 ]
- Interferon-inducible double stranded rna-dependent protein kinase activator a (34 kDa, Protein from Homo sapiens)
- Endoribonuclease dicer (220 kDa, Protein from Homo sapiens)
- Human dicer-pact heterodimer in closed conformation (260 kDa, Sample)