EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Shigematsu H" AND release_date:[2020-01-01T00:00:00Z TO 2020-12-31T23:59:59Z] AND current_status:"REL" AND xref_links:"alphafold" AND microscope_name:"TFS KRIOS" AND natural_source_ncbi_code:"9544"

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EMD-30002

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Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form

Release date: Nov. 11, 2020
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6lw1
Q-score: 0.54

Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T

Nat Commun (2020) 11 pp. 5204-5204 [ DOI: doi:10.1038/s41467-020-19025-z Pubmed: 33060576 ]

Sample:

Tlr7/cpd-7 (dsr-139970) complex (200 kDa, Complex from Macaca mulatta)
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[4-[[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purine (487 Da, Ligand)
Toll-like receptor 7 (94 kDa, Protein from Macaca mulatta)

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