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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Turk M"

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EMD-29339

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Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 monomer state

Release date: Jan. 3, 2024
Resolution: 4.13 Å
EM Method: Single-particle
Fitted PDBs: 8fo2
Q-score: 0.333

Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J

Science (2023) 382 pp. 1404-1411 [ Pubmed: 38127736 DOI: doi:10.1126/science.adi9926 ]

Sample:

Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Guanosine-5'-diphosphate (443 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Ras-related protein rab-7l1 (20 kDa, Protein from Homo sapiens)
Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
Lrrk2-rab29 (Complex from Homo sapiens)

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EMD-29341

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Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 dimer state

Release date: Jan. 3, 2024
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 8fo8
Q-score: 0.264

Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J

Science (2023) 382 pp. 1404-1411 [ Pubmed: 38127736 DOI: doi:10.1126/science.adi9926 ]

Sample:

Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Guanosine-5'-diphosphate (443 Da, Ligand)
Rab29-lrrk2 (Complex from Homo sapiens)
Ras-related protein rab-7l1 (20 kDa, Protein from Homo sapiens)

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EMD-29342

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Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 tetramer state

Release date: Jan. 3, 2024
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8fo9
Q-score: 0.307

Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J

Science (2023) 382 pp. 1404-1411 [ Pubmed: 38127736 DOI: doi:10.1126/science.adi9926 ]

Sample:

Adenosine-5'-triphosphate (507 Da, Ligand)
Ras-related protein rab-7l1 (20 kDa, Protein from Homo sapiens)
Guanosine-5'-diphosphate (443 Da, Ligand)
Rab29-lrrk2 (Complex from Homo sapiens)
Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)

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EMD-40588

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Cryo-EM structure of LRRK2 bound with type-I inhibitor DNL201

Release date: Jan. 3, 2024
Resolution: 4.02 Å
EM Method: Single-particle
Fitted PDBs: 8smc
Q-score: 0.435

Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J

Science (2023) 382 pp. 1404-1411 [ Pubmed: 38127736 DOI: doi:10.1126/science.adi9926 ]

Sample:

Non-specific serine/threonine protein kinase (136 kDa, Protein from Homo sapiens)
2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1h-pyrazol-1-yl)propanenitrile (339 Da, Ligand)
Guanosine-5'-diphosphate (443 Da, Ligand)
Lrrk2 (Complex from Homo sapiens)

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EMD-0137

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Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - 70S Hibernating E. coli Ribosome

Release date: Sept. 5, 2018
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6h4n
Q-score: 0.523

Beckert B, Turk M, Czech A, Berninghausen O, Beckmann R, Ignatova Z, Plitzko JM, Wilson DN

Nat Microbiol (2018) 3 pp. 1115-1121 [ DOI: doi:10.1038/s41564-018-0237-0 Pubmed: 30177741 ]

Sample:

50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l15 (14 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s6 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BW25113)
Ribosome modulation factor (6 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BW25113)
Structure of a hibernating 100s ribosome reveals an inactive conformation of the ribosomal protein s1 (Complex from Escherichia coli BW25113)
50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BW25113)
5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
Ribosome hibernation promoting factor (10 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BW25113)
23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
Trna (24 kDa, RNA from Escherichia coli BW25113)
30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli BW25113)
Rna (5'-r(p*cp*up*cp*cp*u)-3') (1 kDa, RNA from Escherichia coli BW25113)
30s ribosomal protein s1 (61 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s7 (18 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s2 (24 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s21 (7 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l27 (8 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli BW25113)

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EMD-0139

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Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome

Release date: Sept. 5, 2018
Resolution: 7.9 Å
EM Method: Single-particle
Fitted PDBs: 6h58
Q-score: 0.122

Beckert B, Turk M, Czech A, Berninghausen O, Beckmann R, Ignatova Z, Plitzko JM, Wilson DN

Nat Microbiol (2018) 3 pp. 1115-1121 [ DOI: doi:10.1038/s41564-018-0237-0 Pubmed: 30177741 ]

Sample:

50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l15 (14 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s6 (11 kDa, Protein from Escherichia coli BW25113)
Ribosome modulation factor (6 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli BW25113)
Structure of a hibernating 100s ribosome reveals an inactive conformation of the ribosomal protein s1 (Complex from Escherichia coli BW25113)
50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BW25113)
5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
Ribosome hibernation promoting factor (10 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BW25113)
16s ribosomal rna (498 kDa, RNA from Escherichia coli BW25113)
50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s1 (61 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s7 (18 kDa, Protein from Escherichia coli BW25113)
Trna mixture (24 kDa, RNA from Escherichia coli BW25113)
50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s2 (25 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l27 (8 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s21 (7 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli BW25113)
50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BW25113)
30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli BW25113)

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EMD-8143

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nuclear ribo-nucleoprotein complex

Release date: Aug. 3, 2016
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 5jpq
Q-score: 0.097

Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D, Kos-Braun I, Kos M, Thoms M, Berninghausen O, Beckmann R, Hurt E

Cell (2016) 166 pp. 380-393 [ Pubmed: 27419870 DOI: doi:10.1016/j.cell.2016.06.014 ]

Sample:

Nuclear ribo-nucleoprotein complex (Complex from Chaetomium thermophilum)

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Showing 1 - 7 of 7. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [7]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

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