Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7lx5
Q-score: 0.478
Pymm P, Adair A, Chan LJ, Cooney JP, Mordant FL, Allison CC, Lopez E, Haycroft ER, O'Neill MT, Tan LL, Dietrich MH, Drew D, Doerflinger M, Dengler MA, Scott NE, Wheatley AK, Gherardin NA, Venugopal H, Cromer D, Davenport MP, Pickering R, Godfrey DI, Purcell DFJ, Kent SJ, Chung AW, Subbarao K, Pellegrini M, Glukhova A, Tham WH
PNAS (2021) 118 [ Pubmed: 33893175 DOI: doi:10.1073/pnas.2101918118 ]
- Sars-cov-2 spike protein receptor binding domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Wnb 2 (14 kDa, Protein from Vicugna pacos)
- Neutralizing nanobodies wnb 2 and wnb 10 (Complex from Vicugna pacos)
- Wnb 10 (13 kDa, Protein from Vicugna pacos)
- Spike glycoprotein (152 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Focused refinement of the sars-cov-2 spike protein receptor binding domain bound to neutralizing nanobodies wnb 2 and wnb 10 (Complex)
Pymm P, Adair A, Chan LJ, Cooney JP, Mordant FL, Allison CC, Lopez E, Haycroft ER, O'Neill MT, Tan LL, Dietrich MH, Drew D, Doerflinger M, Dengler MA, Scott NE, Wheatley AK, Gherardin NA, Venugopal H, Cromer D, Davenport MP, Pickering R, Godfrey DI, Purcell DFJ, Kent SJ, Chung AW, Subbarao K, Pellegrini M, Glukhova A, Tham WH
PNAS (2021) 118 [ Pubmed: 33893175 DOI: doi:10.1073/pnas.2101918118 ]
- Wnb2 (Protein from Vicugna pacos)
- Neutralising nanobodies wnb2 and wnb10 (Complex from Vicugna pacos)
- Sars-cov-2 spike protein (Complex from evere acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em map of sars-cov-2 spike protein bound to neutralising nanobodies wnb2 and wnb10 (c3 symmetry) (Complex)
- Wnb10 (Protein from Vicugna pacos)
Pymm P, Adair A, Chan LJ, Cooney JP, Mordant FL, Allison CC, Lopez E, Haycroft ER, O'Neill MT, Tan LL, Dietrich MH, Drew D, Doerflinger M, Dengler MA, Scott NE, Wheatley AK, Gherardin NA, Venugopal H, Cromer D, Davenport MP, Pickering R, Godfrey DI, Purcell DFJ, Kent SJ, Chung AW, Subbarao K, Pellegrini M, Glukhova A, Tham WH
PNAS (2021) 118 [ Pubmed: 33893175 DOI: doi:10.1073/pnas.2101918118 ]
- Wnb2 (Protein from Vicugna pacos)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Wnb10 (Protein from Vicugna pacos)
- Cryo-em map of sars-cov-2 spike protein in complex with neutralising nanobodies wnb2 and wnb10 (c1 symmetry) (Complex)
- Sars-cov-2 spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Neutralising nanobodies wnb2 and wnb10 (Complex from Vicugna pacos)