Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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EMD-14737

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Cryo-EM structure of the human INO80 complex bound to a WT nucleosome

Release date: April 19, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7zi4
Q-score: 0.462

Vance NR, Ayala R, Willhoft O, Tvardovskiy A, McCormack EA, Bartke T, Zhang X, Wigley DB

To Be Published

Sample:

Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
Histone h4 (11 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Chromatin-remodeling atpase ino80 (177 kDa, Protein from Homo sapiens)
Dna (158-mer) (48 kDa, DNA from synthetic construct)
Actin-related protein 5 (68 kDa, Protein from Homo sapiens)
Beryllium trifluoride ion (66 Da, Ligand)
Histone h3.1 (15 kDa, Protein from Homo sapiens)
Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
Dna (158-mer) (48 kDa, DNA from synthetic construct)
Adenosine-5'-diphosphate (427 Da, Ligand)
Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
Ino80 complex subunit c (20 kDa, Protein from Homo sapiens)
Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
Complex of human ino80core bound to a wt nucleosome (1 MDa, Complex from Homo sapiens)
Ino80 complex subunit b (38 kDa, Protein from Homo sapiens)

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EMD-3773

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High resolution INO80 core complex

Release date: Dec. 13, 2017
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 5oaf
Q-score: 0.315

Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang X

Nat Struct Mol Biol (2018) 25 pp. 37-44 [ Pubmed: 29323271 DOI: doi:10.1038/s41594-017-0003-7 ]

Sample:

Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
Human ino80 core complex (800 kDa, Complex from Homo sapiens)
Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)

[Show more]

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