EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Zeng L" AND xref_links:"chembl"

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EMD-33387

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Structure of hSLC19A1+3'3'-CDA

Release date: Oct. 5, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7xq0
Q-score: 0.558

Zhang Q, Zhang X, Zhu Y, Sun P, Zhang L, Ma J, Zhang Y, Zeng L, Nie X, Gao Y, Li Z, Liu S, Lou J, Gao A, Zhang L, Gao P

Nature (2022) 612 pp. 170-176 [ DOI: doi:10.1038/s41586-022-05452-z Pubmed: 36265513 ]

Sample:

EMD-33389

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Structure of hSLC19A1+2'3'-cGAMP

Release date: Oct. 5, 2022
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7xq2
Q-score: 0.538

Zhang Q, Zhang X, Zhu Y, Sun P, Zhang L, Ma J, Zhang Y, Zeng L, Nie X, Gao Y, Li Z, Liu S, Lou J, Gao A, Zhang L, Gao P

Nature (2022) 612 pp. 170-176 [ Pubmed: 36265513 DOI: doi:10.1038/s41586-022-05452-z ]

Sample:

Cgamp (674 Da, Ligand)
Slc19a1+2'3'-cgamp (Complex from Homo sapiens)
Reduced folate transporter (60 kDa, Protein from Homo sapiens)

EMD-34176

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Structure of hSLC19A1+5-MTHF

Release date: Oct. 5, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8goe
Q-score: 0.581

Zhang Q, Zhang X, Zhu Y, Sun P, Zhang L, Ma J, Zhang Y, Zeng L, Nie X, Gao Y, Li Z, Liu S, Lou J, Gao A, Zhang L, Gao P

Nature (2022) 612 pp. 170-176 [ DOI: doi:10.1038/s41586-022-05452-z Pubmed: 36265513 ]

Sample:

N-[4-({[(6s)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-l-glutamic acid (459 Da, Ligand)
Slc19a1+5-mthf (Complex from Homo sapiens)
Reduced folate transporter (60 kDa, Protein from Homo sapiens)

EMD-34177

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Structure of hSLC19A1+PMX

Release date: Oct. 5, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8gof
Q-score: 0.577

Zhang Q, Zhang X, Zhu Y, Sun P, Zhang L, Ma J, Zhang Y, Zeng L, Nie X, Gao Y, Li Z, Liu S, Lou J, Gao A, Zhang L, Gao P

Nature (2022) 612 pp. 170-176 [ DOI: doi:10.1038/s41586-022-05452-z Pubmed: 36265513 ]

Sample:

2-{4-[2-(2-amino-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]-benzoylamino}-pentanedioic acid (427 Da, Ligand)
Slc19a1+pmx (Complex from Homo sapiens)
Reduced folate transporter (60 kDa, Protein from Homo sapiens)

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EMDB [4]

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