Structure of CRL2APPBP2 bound with RxxGP degron (dimer)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8jal
Q-score: 0.473
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Elongin-c (12 kDa, Protein from Homo sapiens)
- Leu-thr-arg-asn-lys-gly-pro (1 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)
Structure of CRL2APPBP2 bound with RxxGP degron (tetramer)
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8jaq
Q-score: 0.443
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Xp_211896 c-degron (1 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8jar
Q-score: 0.468
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Xp_211896+aa c-degron (1 kDa, Protein from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer)
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8jas
Q-score: 0.366
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Sumo-xp_211896+aa c-degron (1 kDa, Protein from Homo sapiens)
Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8jau
Q-score: 0.478
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Mrpl28 c-degron (1 kDa, Protein from Homo sapiens)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer)
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8jav
Q-score: 0.421
Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C
PNAS (2023) 120 pp. e2308870120-e2308870120 [ DOI: doi:10.1073/pnas.2308870120 Pubmed: 37844242 ]
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Crl2appbp2 e3 liganse (400 MDa, Complex from Homo sapiens)
- Mrpl28 c-degron (1 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Amyloid protein-binding protein 2 (66 kDa, Protein from Homo sapiens)