In situ structure of the non-replicative Chikungunya virus nonstructural protein complex
Tan YB, Chmielewski D, Law MCY, Zhang K, He Y, Chen M, Jin J, Luo D
Sci Adv (2022) 8 pp. eadd2536-eadd2536 [ Pubmed: 36449616 DOI: doi:10.1126/sciadv.add2536 ]
In situ structure of the Chikungunya virus replication complex
Tan YB, Chmielewski D, Law MCY, Zhang K, He Y, Chen M, Jin J, Luo D
Sci Adv (2022) 8 pp. eadd2536-eadd2536 [ Pubmed: 36449616 DOI: doi:10.1126/sciadv.add2536 ]
Cryo-EM structure of full-length TRPV1 at pH6a state
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7l2i
Q-score: 0.409
Cell (2021) 184 pp. 5138- [ DOI: doi:10.1016/j.cell.2021.08.012 Pubmed: 34496225 ]
- Full-length trpv1 in nanodisc at ph6a state (Complex from Rattus norvegicus)
- (2s)-1-(butanoyloxy)-3-{[(r)-hydroxy{[(1s,2r,3r,4r,5r,6s)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate (600 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 1 (95 kDa, Protein from Rattus norvegicus)
Cryo-EM structure of full-length TRPV1 at pH6c state
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 7l2j
Q-score: 0.395
Cell (2021) 184 pp. 5138- [ DOI: doi:10.1016/j.cell.2021.08.012 Pubmed: 34496225 ]
- (2s)-1-(butanoyloxy)-3-{[(r)-hydroxy{[(1r,2r,3s,4s,5r,6s)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate (600 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 1 (95 kDa, Protein from Rattus norvegicus)
- Full-length trpv1 in nanodisc (Complex from Rattus norvegicus)
Cryo-EM structure of full-length TRPV1 at pH6b state
Resolution: 3.89 Å
EM Method: Single-particle
Fitted PDBs: 7l2k
Q-score: 0.335
Cell (2021) 184 pp. 5138- [ DOI: doi:10.1016/j.cell.2021.08.012 Pubmed: 34496225 ]
Cryo-EM structure of RTX-bound full-length TRPV1 at pH 5.5
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 7l2o
Q-score: 0.393
Cell (2021) 184 pp. 5138- [ DOI: doi:10.1016/j.cell.2021.08.012 Pubmed: 34496225 ]
Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R
Nat Methods (2020) 17 pp. 699-707 [ Pubmed: 32616928 DOI: doi:10.1038/s41592-020-0878-9 ]
- Rna (130-mer) (42 kDa, RNA from synthetic construct)
- Atp-ttr-3 with amp (42 kDa, Complex from synthetic construct)
Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R
Nat Methods (2020) 17 pp. 699-707 [ Pubmed: 32616928 DOI: doi:10.1038/s41592-020-0878-9 ]
- Rna (130-mer) (42 kDa, RNA from synthetic construct)
- Apo atp-ttr-3 (42 kDa, Complex from synthetic construct)
Apo F. nucleatum glycine riboswitch
Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R
Nat Methods (2020) 17 pp. 699-707 [ Pubmed: 32616928 DOI: doi:10.1038/s41592-020-0878-9 ]
- Apo f. nucleatum glycine riboswitch (56 kDa, Complex from Fusobacterium nucleatum)
- Rna (171-mer) (55 kDa, RNA from Fusobacterium nucleatum)