Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondriain-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofaSus scrofa)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Ubiquinone-10 (863 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Ubiquinone-10 (863 Da, Ligand)
- Heme c (618 Da, Ligand)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Sus scrofa)
In-situ complex III, state III
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Ubiquinone-10 (863 Da, Ligand)
- Heme c (618 Da, Ligand)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Sus scrofa)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Ubiquinone-10 (863 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
High resolution in-situ structure of complex III in respiratory supercomplex (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Water (18 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Sus scrofa)
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 8jce
Q-score: 0.643
Law MCY, Zhang K, Tan YB, Nguyen TM, Luo D
J Biol Chem (2023) 299 pp. 105415-105415 [ DOI: doi:10.1016/j.jbc.2023.105415 Pubmed: 37918803 ]
- Magnesium ion (24 Da, Ligand)
- [(2~{r},3~{r},4~{r},5~{r})-5-(6-azanyl-7,8-dihydropurin-9-yl)-2-[[[[[(2~{r},3~{s},4~{r},5~{r})-5-(2-azanyl-7-methyl-6-oxidanylidene-1,8-dihydropurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-4-methoxy-oxolan-3-yl] [(2~{r},3~{s},4~{r},5~{s})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (1 kDa, Ligand)
- Water (18 Da, Ligand)
- Mrna-capping enzyme nsp1 (61 kDa, Protein from Chikungunya virus strain S27-African prototype)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nonstructural protein 1 (Complex from Chikungunya virus strain S27-African prototype)
Spiral hexamer of the substrate-free Lon protease with a Y224S mutation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7ypi
Q-score: 0.144
Li S, Hsieh KY, Kuo CI, Lin TC, Lee SH, Chen YR, Wang CH, Ho MR, Ting SY, Zhang K, Chang CI
Nat Commun (2023) 14 pp. 7340-7340 [ Pubmed: 37957149 DOI: doi:10.1038/s41467-023-43035-2 ]
- Homo-hexameric complex of lon protease with atpgammas (530 kDa, Complex from Meiothermus taiwanensis)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Lon protease (88 kDa, Protein from Meiothermus taiwanensis)
Close-ring hexamer of the substrate-bound Lon protease with an S678A mutation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ypk
Q-score: 0.231
Li S, Hsieh KY, Kuo CI, Lin TC, Lee SH, Chen YR, Wang CH, Ho MR, Ting SY, Zhang K, Chang CI
Nat Commun (2023) 14 pp. 7340-7340 [ Pubmed: 37957149 DOI: doi:10.1038/s41467-023-43035-2 ]
- Alpha-s1-casein (1 kDa, Protein from Bos taurus)
- Close-ring hexamer of mtalon-s678a in a substrate-engaged state (530 kDa, Complex from Bos taurus)
- Lon protease (88 kDa, Protein from Meiothermus taiwanensis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Alpha-s1-casein (Complex from Meiothermus taiwanensis)
- Close-ring hexamer of lon protease (Complex)
MtaLon-Apo for the spiral oligomers of hexamer
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7yut
Q-score: 0.233
Li S, Hsieh KY, Kuo CI, Lin TC, Lee SH, Chen YR, Wang CH, Ho MR, Ting SY, Zhang K, Chang CI
Nat Commun (2023) 14 pp. 7340-7340 [ DOI: doi:10.1038/s41467-023-43035-2 Pubmed: 37957149 ]
- Mtalon-apo for the spiral oligomers of hexamer (600 kDa, Complex from Meiothermus taiwanensis)
- Lon protease (88 kDa, Protein from Meiothermus taiwanensis)
MtaLon-ADP for the spiral oligomers of hexamer
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yux
Q-score: 0.265
Li S, Hsieh KY, Kuo CI, Lin TC, Lee SH, Chen YR, Wang CH, Ho MR, Ting SY, Zhang K, Chang CI
Nat Commun (2023) 14 pp. 7340-7340 [ DOI: doi:10.1038/s41467-023-43035-2 Pubmed: 37957149 ]
- Mtalon-apo for the spiral oligomers of hexamer (600 kDa, Complex from Meiothermus taiwanensis)
- Lon protease (88 kDa, Protein from Meiothermus taiwanensis)
- Adenosine-5'-diphosphate (427 Da, Ligand)