AP2 bound to MSP1 nanodisc with Tgn38 cargo peptide
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ Pubmed: 37364761 DOI: doi:10.1016/j.jsb.2023.107989 ]
- Ap-2 complex subunit beta (Protein from Mus musculus)
- Ap-2 complex (Complex from Mus musculus)
- Ap-2 complex subunit mu (Protein from Mus musculus)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Tgn38 tyrosine cargo peptide (Protein from Rattus norvegicus)
- Ap2 bound to msp1 nanodisc with tgn38 cargo peptide (200 kDa, Complex)
- Tgn38 cargo peptide (Complex)
- Ap-2 complex subunit alpha-2 (Protein from Mus musculus)
AP2 bound to MSP1E3D1 nanodisc with Tgn38 cargo peptide
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ Pubmed: 37364761 DOI: doi:10.1016/j.jsb.2023.107989 ]
- Ap2 bound to msp1e3d1 nanodisc and tgn38 cargo peptide (200 kDa, Complex)
- Ap-2 complex subunit beta (Protein from Mus musculus)
- Ap-2 complex (Complex from Mus musculus)
- Ap-2 complex subunit mu (Protein from Mus musculus)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Tgn38 (Protein from Rattus norvegicus)
- Tgn38 cargo peptide (Complex)
- Ap-2 complex subunit alpha-2 (Protein from Mus musculus)
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ DOI: doi:10.1016/j.jsb.2023.107989 Pubmed: 37364761 ]
- Ap-2 complex subunit mu (Protein from Mus musculus)
- Msp1 (Protein from Homo sapiens)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Ap-2 complex subunit beta (Protein from Mus musculus)
- Ap2 bound to msp2n2 nanodisc (203 kDa, Complex from Mus musculus)
- Ap-2 complex subunit alpha-2 (Protein from Mus musculus)
Structure of AP2 bound to MSP1E3D1 nanodisc
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ Pubmed: 37364761 DOI: doi:10.1016/j.jsb.2023.107989 ]
- Ap-2 complex subunit beta (Protein from Mus musculus)
- Msp2n2 (Protein from Homo sapiens)
- Ap-2 complex subunit mu (Protein from Mus musculus)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Ap2 bound to msp1e3d1 nanodisc (203 kDa, Complex from Mus musculus)
- Ap-2 complex subunit alpha-2 (Protein from Mus musculus)
Structure of AP2 bound to MSP2N2 nanodisc
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ DOI: doi:10.1016/j.jsb.2023.107989 Pubmed: 37364761 ]
- Ap-2 complex subunit mu (Protein from Mus musculus)
- Msp1e3d1 (Protein from Homo sapiens)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Ap-2 complex subunit beta (Protein from Mus musculus)
- Ap2 bound to msp2n2 nanodisc (203 kDa, Complex from Mus musculus)
- Ap-2 complex subunit alpha-2 (Protein from Mus musculus)
AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8t1o
Q-score: 0.468
S Cannon K, Sarsam RD, Tedamrongwanish T, Zhang K, Baker RW
J Struct Biol (2023) 215 pp. 107989-107989 [ Pubmed: 37364761 DOI: doi:10.1016/j.jsb.2023.107989 ]
- Ap-2 complex subunit alpha-2 (70 kDa, Protein from Mus musculus)
- Ap-2 complex subunit beta (66 kDa, Protein from Mus musculus)
- Ap-2 complex subunit sigma (17 kDa, Protein from Mus musculus)
- Trans-golgi network integral membrane protein tgn38 (1 kDa, Protein from Rattus norvegicus)
- Ap2 bound to msp2n2 nanodisc with tgn38 cargo peptide (200 kDa, Complex from Mus musculus)
- Ap-2 complex subunit mu (49 kDa, Protein from Mus musculus)
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ytw
Q-score: 0.507
Wang M, He J, Li S, Cai Q, Zhang K, She J
Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]
- Ascorbic acid (176 Da, Ligand)
- Water (18 Da, Ligand)
- Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)
- Svct1 (Complex from Mus musculus)
- Sodium ion (22 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yty
Q-score: 0.447
Wang M, He J, Li S, Cai Q, Zhang K, She J
Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]
- Svct1 (Complex from Mus musculus)
- Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)
Human Thyrotropin receptor bound by CS-17 Inverse Agonist Fab/Org 274179-0 Antagonist
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7t9m
Q-score: 0.396
Faust B, Billesbolle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A
Nature (2022) 609 pp. 846-853 [ Pubmed: 35940205 DOI: doi:10.1038/s41586-022-05159-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human thyrotropin receptor in complex with the murine inverse agonist fab fragment cs-17 (Complex from Homo sapiens)
- Thyrotropin receptor (79 kDa, Protein from Homo sapiens)
- Cs-17 light chain (23 kDa, Protein from Mus musculus)
- Cs-17 heavy chain (23 kDa, Protein from Mus musculus)
Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8cxo
Q-score: 0.386
Zhang K, Wu H, Hoppe N, Manglik A, Cheng Y
Nat Commun (2022) 13 pp. 4366-4366 [ DOI: doi:10.1038/s41467-022-32125-2 Pubmed: 35902590 ]
- Smoothened homolog, glga glycogen synthase chimera (80 kDa, Protein from Mus musculus)
- Cholesterol (386 Da, Ligand)
- Msmo-pgs2 (Complex from Mus musculus)