Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8if8
Q-score: 0.552
Gong Y, Wei C, Wang J, Mu N, Lu Q, Wu C, Yan N, Yang H, Zhao Y, Yang X, Gurcha SS, Veerapen N, Batt SM, Hao Z, Da L, Besra GS, Rao Z, Zhang L
PNAS (2023) 120 pp. e2302858120-e2302858120 [ Pubmed: 37252995 DOI: doi:10.1073/pnas.2302858120 ]
- Galactan 5-o-arabinofuranosyltransferase (69 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Calcium ion (40 Da, Ligand)
- Afta dimer (69 kDa, Complex from Mycobacterium tuberculosis H37Rv)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7bvc
Q-score: 0.564
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Emba-embb (Complex from Mycolicibacterium smegmatis MC2 155)
- [(2z,6e,10e,14z,18e,22z,26z)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2s,3s,4s,5r)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate (911 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embb (119 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Integral membrane indolylacetylinositol arabinosyltransferase emba (116 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- 4'-phosphopantetheine (358 Da, Ligand)
- Mycobacterium smegmatis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Phosphate ion (94 Da, Ligand)
- Ethambutol (204 Da, Ligand)
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7bve
Q-score: 0.552
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Embc (Complex from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- N~3~-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-n-(2-sulfanylethyl)-beta-alaninamide (358 Da, Ligand)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Mycobacterium smegmatis arabinosyltransferase embc2-acpm2 in complex with ethambutol (Complex)
- Phosphate ion (94 Da, Ligand)
- Ethambutol (204 Da, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embc (116 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7bvf
Q-score: 0.58
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Mycobacterium tuberculosis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Emba and embb (Complex from Mycobacterium tuberculosis H37Rv)
- Cardiolipin (1 kDa, Ligand)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Probable arabinosyltransferase a (116 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Ethambutol (204 Da, Ligand)
- Mono-trans, octa-cis decaprenyl-phosphate (779 Da, Ligand)
- Probable arabinosyltransferase b (120 kDa, Protein from Mycobacterium tuberculosis H37Rv)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7bvg
Q-score: 0.537
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Mycobacterium smegmatis arabinosyltransferase emba-embb-acpm2 in complex with di-arabinose (Complex)
- [(2z,6e,10e,14z,18e,22z,26z)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2s,3s,4s,5r)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate (911 Da, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embb (119 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Cardiolipin (1 kDa, Ligand)
- Emba and embb (Complex from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Integral membrane indolylacetylinositol arabinosyltransferase emba (116 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- 4'-phosphopantetheine (358 Da, Ligand)