Electron Microscopy Data Bank

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cryoEM reconstruction of 3BC315 Fab in complex with BG505 SOSIP.664 Env trimer

Release date: Oct. 7, 2015
Resolution: 9.3 Å
EM Method: Single-particle

Lee JH, Leaman DP, Kim AS, Torrents de la Pena A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, Klasse PJ, Sanders RW, Zwick MB, Wilson IA, Ward AB

Nat Commun (2015) 6 pp. 8167-8167 [ DOI: doi:10.1038/ncomms9167 Pubmed: 26404402 ]

Sample:

3bc315 fab in complex with bg505 sosip.664 trimer (520 kDa, Sample)
Hiv-1 envelope glycoprotein (420 kDa, Protein)
3bc315 antibody fab (500 kDa, Protein from Homo sapiens)

EMD-2853

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3BNC117 Fab in complex with BG505 SOSIP.664 Trimer

Release date: March 11, 2015
Resolution: 20.0 Å
EM Method: Single-particle

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW

PLoS Pathog (2015) 11 pp. e1004767-e1004767 [ Pubmed: 25807248 DOI: doi:10.1371/journal.ppat.1004767 ]

Sample:

Fab of 3bnc117 monoclonal antibody bound to recombinant hiv-1 env gp140 bg505 sosip.664 trimer (570 kDa, Sample)
Soluble hiv-1 envelope glycoprotein (420 kDa, Protein from Human immunodeficiency virus 1)
Fab of 3bnc117 human monoclonal antibody (50 kDa, Protein from Homo sapiens)

EMD-6249

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1NC9 Fab in complex with BG505 SOSIP.664 Trimer

Release date: March 11, 2015
Resolution: 18.0 Å
EM Method: Single-particle

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW

PLoS Pathog (2015) 11 pp. e1004767-e1004767 [ DOI: doi:10.1371/journal.ppat.1004767 Pubmed: 25807248 ]

Sample:

Soluble hiv-1 envelope glycoprotein (420 kDa, Protein from Human immunodeficiency virus 1)
Fab of 1nc9 human monoclonal antibody (50 kDa, Protein from Homo sapiens)
Fab of 1nc9 human monoclonal antibody bound to hiv-1 env gp140 bg505 sosip.664 (570 kDa, Sample)

EMD-6250

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CH103 Fab in complex with BG505 SOSIP.664 Trimer

Release date: March 11, 2015
Resolution: 15.0 Å
EM Method: Single-particle

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW

PLoS Pathog (2015) 11 pp. e1004767-e1004767 [ Pubmed: 25807248 DOI: doi:10.1371/journal.ppat.1004767 ]

Sample:

Fab of ch103 human monoclonal antibody (50 kDa, Protein from Homo sapiens)
Fab of ch103 human monoclonal antibody bound to hiv-1 env gp140 bg505 sosip.664 (570 kDa, Sample)
Soluble hiv-1 envelope glycoprotein (420 kDa, Protein from Human immunodeficiency virus 1)

EMD-6251

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CH106 Fab in complex with BG505 SOSIP.664 Trimer

Release date: March 11, 2015
Resolution: 19.0 Å
EM Method: Single-particle

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW

PLoS Pathog (2015) 11 pp. e1004767-e1004767 [ DOI: doi:10.1371/journal.ppat.1004767 Pubmed: 25807248 ]

Sample:

Soluble hiv-1 envelope glycoprotein (420 kDa, Protein from Human immunodeficiency virus 1)
Fab of ch106 human monoclonal antibody (50 kDa, Protein from Homo sapiens)
Fab of ch106 human monoclonal antibody bound to hiv-1 env gp140 bg505 sosip.664 (570 kDa, Sample)

EMD-6252

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VRC01 Fab in complex with BG505 SOSIP.664 Trimer

Release date: March 11, 2015
Resolution: 22.0 Å
EM Method: Single-particle

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW

PLoS Pathog (2015) 11 pp. e1004767-e1004767 [ DOI: doi:10.1371/journal.ppat.1004767 Pubmed: 25807248 ]

Sample:

Soluble hiv-1 envelope glycoprotein (420 kDa, Protein from Human immunodeficiency virus 1)
Fab of vrc01 human monoclonal antibody bound to hiv-1 env gp140 bg505 sosip.664 (570 kDa, Sample)
Fab of vrc01 human monoclonal antibody (50 kDa, Protein from Homo sapiens)

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