Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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proteasome* AND xref_links:"pfam" AND author_name:"Peng C" AND assembly_molecular_weight:{250000 TO 500000] AND sample_type:"complex"

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EMD-34474

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Cryo-EM Structure of the KBTBD2-CRL3~N8 dimeric complex

Release date: Oct. 11, 2023
Resolution: 6.36 Å
EM Method: Single-particle
Fitted PDBs: 8h3r
Q-score: 0.04

Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L

Nat Struct Mol Biol (2024) 31 pp. 336-350 [ DOI: doi:10.1038/s41594-023-01182-6 Pubmed: 38332366 ]

Sample:

E3 ubiquitin-protein ligase rbx1 (12 kDa, Protein from Homo sapiens)
Cullin-3 (89 kDa, Protein from Homo sapiens)
Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
Kbtbd2-crl3~n8 dimeric complex (Complex from Homo sapiens)
Zinc ion (65 Da, Ligand)

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EMD-34199

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Cryo-EM Structure of the KBTBD2-CUL3-Rbx1 dimeric complex

Release date: Sept. 6, 2023
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8gq6
Q-score: 0.176

Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L

Nat Struct Mol Biol (2024) 31 pp. 336-350 [ DOI: doi:10.1038/s41594-023-01182-6 Pubmed: 38332366 ]

Sample:

Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
E3 ubiquitin-protein ligase rbx1 (13 kDa, Protein from Homo sapiens)
Cullin-3 (90 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Kbtbd2-cul3-rbx1 dimeric complex (Complex from Homo sapiens)

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EMDB [2]

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