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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"23 kDa U4/U6.U5 small nuclear ribonucleoprotein component"

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EMD-6974

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Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom

Release date: Aug. 29, 2018
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5zwo
Q-score: 0.191

Bai R, Wan R, Yan C, Lei J, Shi Y

Science (2018) 360 pp. 1423-1429 [ Pubmed: 29794219 DOI: doi:10.1126/science.aau0325 ]

Sample:

U4/u6 small nuclear ribonucleoprotein prp4 (52 kDa, Protein from Saccharomyces cerevisiae S288c)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna leakage protein 1 (23 kDa, Protein from Saccharomyces cerevisiae S288c)
23 kda u4/u6.u5 small nuclear ribonucleoprotein component (22 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor spp381 (33 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm8 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm4 (21 kDa, Protein from Saccharomyces cerevisiae S288c)
66 kda u4/u6.u5 small nuclear ribonucleoprotein component (66 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 38 (27 kDa, Protein from Saccharomyces cerevisiae S288c)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Saccharomyces cerevisiae S288c)
Spliceosomal protein dib1 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm3 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U4 snrna (51 kDa, RNA from Saccharomyces cerevisiae S288c)
Magnesium ion (24 Da, Ligand)
Guanosine-5'-triphosphate (523 Da, Ligand)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae S288c)
U2 snrnp component hsh155 (110 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 snrnp component ist3 (17 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 6 (104 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna (19 kDa, RNA from Saccharomyces cerevisiae S288c)
Protein hsh49 (24 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor prp9 (63 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-processing factor 31 (56 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm5 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U4/u6 small nuclear ribonucleoprotein prp3 (55 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
Rds3 complex subunit 10 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm6 (9 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae S288c)
Yeast fully assembled spliceosomal b complex before activation (Cell from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm2 (11 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor cwc26 (30 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm7 (13 kDa, Protein from Saccharomyces cerevisiae S288c)
13 kda ribonucleoprotein-associated protein (13 kDa, Protein from Saccharomyces cerevisiae S288c)

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EMD-3683

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Structure of a pre-catalytic spliceosome (B2 map)

Release date: May 31, 2017
Resolution: 7.2 Å
EM Method: Single-particle
Fitted PDBs: 5nrl
Q-score: 0.117

Plaschka C, Lin PC, Nagai K

Nature (2017) 546 pp. 617-621 [ Pubmed: 28530653 DOI: doi:10.1038/nature22799 ]

Sample:

66 kda u4/u6.u5 small nuclear ribonucleoprotein component (66 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm5 (10 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm6 (9 kDa, Protein from Baker's yeast)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Baker's yeast)
Guanosine-5'-triphosphate (523 Da, Ligand)
U6 snrna-associated sm-like protein lsm7 (13 kDa, Protein from Baker's yeast)
U4/u6 small nuclear ribonucleoprotein prp4 (52 kDa, Protein from Baker's yeast)
U4 snrna (51 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 38 (27 kDa, Protein from Baker's yeast)
Spliceosomal protein dib1 (16 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm4 (21 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
23 kda u4/u6.u5 small nuclear ribonucleoprotein component (22 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor spp381 (33 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm2 (11 kDa, Protein from Baker's yeast)
Zinc ion (65 Da, Ligand)
U4/u6 small nuclear ribonucleoprotein prp3 (55 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 31 (56 kDa, Protein from Baker's yeast)
Unknown (7 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 6 (104 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm8 (12 kDa, Protein from Baker's yeast)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Pre-catalytic b complex spliceosome (2 MDa, Complex from Saccharomyces cerevisiae)
Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
13 kda ribonucleoprotein-associated protein (13 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
Yeast ubc4 gene for ubiquitin-conjugating enzyme (30 kDa, RNA from Saccharomyces cerevisiae)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm3 (10 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae)

[Show more]

Sort by: Download

Showing 1 - 2 of 2. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [2]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: