Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7qh7
Q-score: 0.441
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M
Nat Commun (2022) 13 pp. 929-929 [ Pubmed: 35177605 DOI: doi:10.1038/s41467-022-28503-5 ]
- Peptidyl-trna hydrolase ict1, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (5 kDa, Protein from human)
- 39s ribosomal protein l30, mitochondrial (13 kDa, Protein from human)
- 39s ribosomal protein l38, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (19 kDa, Protein from human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l45, mitochondrial (19 kDa, Protein from human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (11 kDa, Protein from human)
- 39s ribosomal protein l41, mitochondrial (14 kDa, Protein from human)
- 39s ribosomal protein l50, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l15, mitochondrial (32 kDa, Protein from human)
- Ribosomal protein 63, mitochondrial (9 kDa, Protein from human)
- 39s ribosomal protein l34, mitochondrial (5 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- Mitochondrial trnaval (19 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (25 kDa, Protein from human)
- 39s ribosomal protein l18, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein s18a, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l27, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l9, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l42, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l17, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l36, mitochondrial (4 kDa, Protein from human)
- 39s ribosomal protein l37, mitochondrial (45 kDa, Protein from human)
- 39s ribosomal protein l32, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l20, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l48, mitochondrial (2 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (13 kDa, Protein from human)
- 39s ribosomal protein s30, mitochondrial (45 kDa, Protein from human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from human)
- 39s ribosomal protein l21, mitochondrial (17 kDa, Protein from human)
- Acyl carrier protein, mitochondrial (9 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l14, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l49, mitochondrial (15 kDa, Protein from human)
- 16s ribosomal rna (403 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l35, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l10, mitochondrial (3 kDa, Protein from human)
- 39s ribosomal protein l28, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l44, mitochondrial (32 kDa, Protein from human)
- 39s ribosomal protein l47, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l52, mitochondrial (9 kDa, Protein from human)
- 39s ribosomal protein l4, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l51, mitochondrial (11 kDa, Protein from human)
- Water (18 Da, Ligand)
- 39s ribosomal protein l16, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l39, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l43, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l24, mitochondrial (5 kDa, Protein from human)
- Human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (34 kDa, Protein from human)
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7qh6
Q-score: 0.374
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M
Nat Commun (2022) 13 pp. 929-929 [ Pubmed: 35177605 DOI: doi:10.1038/s41467-022-28503-5 ]
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from human)
- Human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from human)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from human)
- 16s ribosomal rna (500 kDa, RNA from human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from human)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from human)
- Mitochondrial trnaval (22 kDa, RNA from human)