Edit your search query here and hit Return to execute it:
sample_name:"4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione"
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Release date: April 19, 2023
Resolution: 2.29 Å
EM Method: Single-particle
Fitted PDBs: 8g5y
Q-score: 0.605
Resolution: 2.29 Å
EM Method: Single-particle
Fitted PDBs: 8g5y
Q-score: 0.605
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC
Nature (2023) 617 pp. 200-207 [ Pubmed: 37020024 DOI: doi:10.1038/s41586-023-05908-w ]
Sample:
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 4-{(2r,5s,6e)-2-hydroxy-5-methyl-7-[(2r,3s,4e,6z,10e)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (457 Da, Ligand)
- Anisomycin (265 Da, Ligand)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- El40 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10a (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- Spermidine (145 Da, Ligand)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- Ul2 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- Human ribosome (Complex from Homo sapiens)
- P-site trna (24 kDa, RNA from Homo sapiens)
- Methionine (149 Da, Ligand)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 1,4-diaminobutane (88 Da, Ligand)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- Mrna (19 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- Eif5a1 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Fau ubiquitin-like and ribosomal protein s30 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- Us12 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 18s rrna (603 kDa, RNA from Homo sapiens)
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Release date: April 19, 2023
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8g5z
Q-score: 0.57
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8g5z
Q-score: 0.57
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC
Nature (2023) 617 pp. 200-207 [ Pubmed: 37020024 DOI: doi:10.1038/s41586-023-05908-w ]
Sample:
- 60s ribosomal protein l34 (12 kDa, Protein from Homo sapiens)
- Plitidepsin (1 kDa, Ligand)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- Ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Us19 (15 kDa, Protein from Homo sapiens)
- 60s acidic ribosomal protein p0 (21 kDa, Protein from Homo sapiens)
- Us9 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (26 kDa, Protein from Homo sapiens)
- Es12 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (17 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (11 kDa, Protein from Homo sapiens)
- Es10 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (25 kDa, Protein from Homo sapiens)
- Us12 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (19 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (11 kDa, Protein from Homo sapiens)
- Methionine (149 Da, Ligand)
- 40s ribosomal protein s3a (25 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s26 (11 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 4-{(2r,5s,6e)-2-hydroxy-5-methyl-7-[(2r,3s,4e,6z,10e)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (457 Da, Ligand)
- 60s ribosomal protein l28 (14 kDa, Protein from Homo sapiens)
- P-site trna fmet (24 kDa, RNA from Escherichia coli)
- 40s ribosomal protein s9 (21 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- El40 (6 kDa, Protein from Homo sapiens)
- 1,4-diaminobutane (88 Da, Ligand)
- 60s ribosomal protein l37 (10 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- El24 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- Es4 (29 kDa, Protein from Homo sapiens)
- Es31 (8 kDa, Protein from Homo sapiens)
- Ul2 (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (16 kDa, Protein from Homo sapiens)
- 18s rrna (549 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- Elongation factor 1-alpha 1 (48 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- Mrna (3 kDa, RNA from Homo sapiens)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (27 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (24 kDa, Protein from Homo sapiens)
- Es27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (41 kDa, Protein from Homo sapiens)
- El6 (25 kDa, Protein from Homo sapiens)
- Anisomycin (265 Da, Ligand)
- Receptor of activated protein c kinase 1 (34 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (15 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Human ribosome 80s with p-site trna, a-site trna eef1a and eif5a1 (5 MDa, Complex)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- A-site trna phe (24 kDa, RNA from Escherichia coli)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 40s ribosomal protein sa (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- Ul23 (13 kDa, Protein from Homo sapiens)
- Us17 (16 kDa, Protein from Homo sapiens)
- Phenylalanine (165 Da, Ligand)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l13 (23 kDa, Protein from Homo sapiens)
- Spermidine (145 Da, Ligand)
- Us13 (17 kDa, Protein from Homo sapiens)
- El29 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10 (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- Es25 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- Eif5a1 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- Us11 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (27 kDa, Protein from Homo sapiens)
- Us10 (11 kDa, Protein from Homo sapiens)
- Ul1 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (10 kDa, Protein from Homo sapiens)
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Release date: April 19, 2023
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8g60
Q-score: 0.576
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8g60
Q-score: 0.576
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC
Nature (2023) 617 pp. 200-207 [ Pubmed: 37020024 DOI: doi:10.1038/s41586-023-05908-w ]
Sample:
- Plitidepsin (1 kDa, Ligand)
- El18 (21 kDa, Protein from Homo sapiens)
- El34 (13 kDa, Protein from Homo sapiens)
- Us3 (26 kDa, Protein from Homo sapiens)
- Us4 (22 kDa, Protein from Homo sapiens)
- El32 (15 kDa, Protein from Homo sapiens)
- Es8 (24 kDa, Protein from Homo sapiens)
- El39 (6 kDa, Protein from Homo sapiens)
- Es4 (29 kDa, Protein from Homo sapiens)
- Us13 (17 kDa, Protein from Homo sapiens)
- Es19 (16 kDa, Protein from Homo sapiens)
- 18s rrna (603 kDa, RNA from Homo sapiens)
- P-site trna (24 kDa, RNA from Homo sapiens)
- Us17 (18 kDa, Protein from Homo sapiens)
- El30 (12 kDa, Protein from Homo sapiens)
- Ul22 (21 kDa, Protein from Homo sapiens)
- Ul16 (24 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Us8 (14 kDa, Protein from Homo sapiens)
- El8 (30 kDa, Protein from Homo sapiens)
- Es12 (14 kDa, Protein from Homo sapiens)
- Us12 (15 kDa, Protein from Homo sapiens)
- El14 (23 kDa, Protein from Homo sapiens)
- Ul29 (14 kDa, Protein from Homo sapiens)
- Es17 (15 kDa, Protein from Homo sapiens)
- El29 (17 kDa, Protein from Homo sapiens)
- Us7 (22 kDa, Protein from Homo sapiens)
- Mrna (19 kDa, RNA from Homo sapiens)
- Methionine (149 Da, Ligand)
- El37 (11 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- Es6 (28 kDa, Protein from Homo sapiens)
- 4-{(2r,5s,6e)-2-hydroxy-5-methyl-7-[(2r,3s,4e,6z,10e)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (457 Da, Ligand)
- Ul4 (47 kDa, Protein from Homo sapiens)
- El15 (24 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Ul13 (23 kDa, Protein from Homo sapiens)
- Es25 (13 kDa, Protein from Homo sapiens)
- Es1 (30 kDa, Protein from Homo sapiens)
- Ul30 (29 kDa, Protein from Homo sapiens)
- 1,4-diaminobutane (88 Da, Ligand)
- El27 (15 kDa, Protein from Homo sapiens)
- Ul15 (16 kDa, Protein from Homo sapiens)
- El21 (18 kDa, Protein from Homo sapiens)
- Us2 (32 kDa, Protein from Homo sapiens)
- Es7 (22 kDa, Protein from Homo sapiens)
- El41 (3 kDa, Protein from Homo sapiens)
- Es21 (9 kDa, Protein from Homo sapiens)
- Es30 (14 kDa, Protein from Homo sapiens)
- Ul23 (17 kDa, Protein from Homo sapiens)
- El43 (10 kDa, Protein from Homo sapiens)
- El22 (14 kDa, Protein from Homo sapiens)
- Ul10 (34 kDa, Protein from Homo sapiens)
- Us11 (16 kDa, Protein from Homo sapiens)
- Ul2 (28 kDa, Protein from Homo sapiens)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- Us5 (31 kDa, Protein from Homo sapiens)
- El13 (31 kDa, Protein from Homo sapiens)
- Us19 (17 kDa, Protein from Homo sapiens)
- El33 (12 kDa, Protein from Homo sapiens)
- Eef1a (50 kDa, Protein from Homo sapiens)
- El6 (32 kDa, Protein from Homo sapiens)
- El36 (12 kDa, Protein from Homo sapiens)
- Anisomycin (265 Da, Ligand)
- Rack1 (35 kDa, Protein from Homo sapiens)
- Ul14 (14 kDa, Protein from Homo sapiens)
- Us15 (17 kDa, Protein from Homo sapiens)
- El28 (15 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- El20 (20 kDa, Protein from Homo sapiens)
- Es27 (9 kDa, Protein from Homo sapiens)
- Human ribosome (Complex from Homo sapiens)
- Ul24 (17 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- Es24 (15 kDa, Protein from Homo sapiens)
- Us9 (16 kDa, Protein from Homo sapiens)
- El19 (23 kDa, Protein from Homo sapiens)
- El31 (14 kDa, Protein from Homo sapiens)
- El42 (12 kDa, Protein from Homo sapiens)
- Ul18 (34 kDa, Protein from Homo sapiens)
- Es10 (18 kDa, Protein from Homo sapiens)
- Ul3 (46 kDa, Protein from Homo sapiens)
- Es31 (18 kDa, Protein from Homo sapiens)
- El24 (17 kDa, Protein from Homo sapiens)
- Es26 (13 kDa, Protein from Homo sapiens)
- Us10 (13 kDa, Protein from Homo sapiens)
- Phenylalanine (165 Da, Ligand)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Spermidine (145 Da, Ligand)
- El40 (14 kDa, Protein from Homo sapiens)
- Us14 (6 kDa, Protein from Homo sapiens)
- Ul1 (24 kDa, Protein from Homo sapiens)
- Ul6 (21 kDa, Protein from Homo sapiens)
- Es28 (7 kDa, Protein from Homo sapiens)
- Ul11 (17 kDa, Protein from Homo sapiens)
- Ul5 (20 kDa, Protein from Homo sapiens)
- A-site trna (24 kDa, RNA from Homo sapiens)
- El38 (8 kDa, Protein from Homo sapiens)
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
Release date: April 19, 2023
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8g61
Q-score: 0.51
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8g61
Q-score: 0.51
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC
Nature (2023) 617 pp. 200-207 [ Pubmed: 37020024 DOI: doi:10.1038/s41586-023-05908-w ]
Sample:
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- Rna (77-mer) (24 kDa, RNA from Escherichia coli)
- 4-{(2r,5s,6e)-2-hydroxy-5-methyl-7-[(2r,3s,4e,6z,10e)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (457 Da, Ligand)
- Anisomycin (265 Da, Ligand)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- El40 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- A-site trna (24 kDa, RNA from Escherichia coli)
- 60s ribosomal protein l10a (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- Spermidine (145 Da, Ligand)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- Ul2 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- Human ribosome (Complex from Homo sapiens)
- Methionine (149 Da, Ligand)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 1,4-diaminobutane (88 Da, Ligand)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- Mrna (19 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- Eif5a1 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Fau ubiquitin-like and ribosomal protein s30 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- Us12 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 18s rrna (603 kDa, RNA from Homo sapiens)
Release date: April 19, 2023
Resolution: 1.67 Å
EM Method: Single-particle
Fitted PDBs: 8glp
Q-score: 0.673
Resolution: 1.67 Å
EM Method: Single-particle
Fitted PDBs: 8glp
Q-score: 0.673
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC
Nature (2023) 617 pp. 200-207 [ Pubmed: 37020024 DOI: doi:10.1038/s41586-023-05908-w ]
Sample:
- 60s ribosomal protein l10 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 18s rrna (603 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- P-site trna (24 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- Mrna (19 kDa, RNA from Homo sapiens)
- Methionine (149 Da, Ligand)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (us12) (15 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 4-{(2r,5s,6e)-2-hydroxy-5-methyl-7-[(2r,3s,4e,6z,10e)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (457 Da, Ligand)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Fau ubiquitin-like and ribosomal protein s30 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (ul2) (28 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 1,4-diaminobutane (88 Da, Ligand)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- Anisomycin (265 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 2-amino-2-hydroxymethyl-propane-1,3-diol (122 Da, Ligand)
- Human ribosome (Complex from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- Spermidine (145 Da, Ligand)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l40 (el40) (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)