EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide"

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EMD-29585

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Vilazodone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex

Release date: May 15, 2024
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8fyl
Q-score: 0.525

Warren AL, Lankri D, Cunningham MJ, Serrano IC, Parise LF, Kruegel AC, Duggan P, Zilberg G, Capper MJ, Havel V, Russo SJ, Sames D, Wacker D

Nature (2024) 630 pp. 237-246 [ Pubmed: 38720072 DOI: doi:10.1038/s41586-024-07403-2 ]

Sample:

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EMD-23545

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Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab

Release date: Aug. 11, 2021
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7lwd
Q-score: 0.466

Plenge P, Yang D, Salomon K, Laursen L, Kalenderoglou IE, Newman AH, Gouaux E, Coleman JA, Loland CJ

Nat Commun (2021) 12 pp. 5063-5063 [ Pubmed: 34417466 DOI: doi:10.1038/s41467-021-25363-3 ]

Sample:

8b6 antibody (Complex from Mus musculus)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Light chain antibody fragment (11 kDa, Protein from Mus musculus)
Sodium-dependent serotonin transporter (61 kDa, Protein from Homo sapiens)
3-(5h-dibenzo[b,f]azepin-5-yl)-n,n-dimethylpropan-1-amine (280 Da, Ligand)
Serotonin transporter 8b6 fab complex (105 kDa, Complex)
Heavy chain antibody fragment (12 kDa, Protein from Mus musculus)
Serotonin transporter (Complex from Homo sapiens)
5-{4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide (441 Da, Ligand)

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Sort by: Download

Showing 1 - 2 of 2. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [2]

Format:

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Shell (Unix-based) Batch (Windows-based)

Preview first 10

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