Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7mit
Q-score: 0.51
Sung MW, Yang Z, Driggers CM, Patton BL, Mostofian B, Russo JD, Zuckerman DM, Shyng SL
PNAS (2021) 118 [ Pubmed: 34711681 DOI: doi:10.1073/pnas.2109441118 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
- Vascular katp channel: kir6.1 sur2b propeller-like conformation 1 (889 kDa, Complex from Rattus norvegicus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- 5-chloro-n-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide (494 Da, Ligand)
- Atp-sensitive inward rectifier potassium channel 8 (48 kDa, Protein from Rattus norvegicus)
Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 1
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7mjo
Q-score: 0.429
Sung MW, Yang Z, Driggers CM, Patton BL, Mostofian B, Russo JD, Zuckerman DM, Shyng SL
PNAS (2021) 118 [ Pubmed: 34711681 DOI: doi:10.1073/pnas.2109441118 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Phosphatidylethanolamine (734 Da, Ligand)
- Vascular katp channel: kir6.1 sur2b quatrefoil-like conformation 2 (889 kDa, Complex from Rattus norvegicus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- 5-chloro-n-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide (494 Da, Ligand)
- Atp-sensitive inward rectifier potassium channel 8 (48 kDa, Protein from Rattus norvegicus)
Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7mjp
Q-score: 0.382
Sung MW, Yang Z, Driggers CM, Patton BL, Mostofian B, Russo JD, Zuckerman DM, Shyng SL
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2109441118 Pubmed: 34711681 ]
- 5-chloro-n-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide (494 Da, Ligand)
- Atp-sensitive inward rectifier potassium channel 8 (48 kDa, Protein from Rattus norvegicus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Vascular katp channel: kir6.1 sur2b propeller-like conformation 2 (889 kDa, Complex from Rattus norvegicus)