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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

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and development of technology

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new instruments and methods

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More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

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Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

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Epigenetics and neurobiology

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sample_name:"BAP1/ASXL1 bound to the H2AK119Ub Nucleosome" AND author_orcid:"0000-0002-2219-8623" AND release_date:[2023-01-01T00:00:00Z TO 2023-12-31T23:59:59Z] AND author_name:"Gloor SL"

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EMDB [3]

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EMD-40789

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BAP1/ASXL1 bound to the H2AK119Ub Nucleosome

Release date: Aug. 30, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8svf
Q-score: 0.383

Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ

Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]

Sample:

Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
Dna/rna (327-mer) (102 kDa, Macromolecule from synthetic construct)
Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)
Histone h3.2 (15 kDa, Protein from Xenopus laevis)
Ubiquitin (8 kDa, Protein from Homo sapiens)
Histone h4 (11 kDa, Protein from Xenopus laevis)
Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)
Polycomb group protein asxl1 (165 kDa, Protein from Homo sapiens)
Dna/rna (187-mer) (58 kDa, Macromolecule from synthetic construct)

[Show more]

EMD-40790

Download Map 3D View

Map focused on acidic patch BAP1/ASXL1 bound to the H2AK119Ub Nucleosome

Release date: Aug. 30, 2023
Resolution: 3.2 Å
EM Method: Single-particle

Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ

Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ DOI: doi:10.1126/sciadv.adg9832 Pubmed: 37556531 ]

Sample:

Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)

EMD-40791

Download Map 3D View

Overall map of BAP1/ASXL1 bound to the H2AK119Ub Nucleosome

Release date: Aug. 30, 2023
Resolution: 3.5 Å
EM Method: Single-particle

Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ

Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ DOI: doi:10.1126/sciadv.adg9832 Pubmed: 37556531 ]

Sample:

Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)

Sort by: Download

Showing 1 - 3 of 3. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [3]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: